血清C'1酯酶抑制剂对纤溶酶、血浆激肽释放酶、血浆通透因子及补体第一成分的C'1r亚成分的抑制作用。
The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C'1r subcomponent of the first component of complement by serum C'1 esterase inhibitor.
作者信息
Ratnoff O D, Pensky J, Ogston D, Naff G B
出版信息
J Exp Med. 1969 Feb 1;129(2):315-31. doi: 10.1084/jem.129.2.315.
Abstract
The fraction of human serum designated as C'1 esterase inhibitor is known to inhibit the action of C'1 esterase, a plasma kallikrein, and PF/Dil, an enzyme in plasma enhancing cutaneous vascular permeability. In the present study, C'1 esterase inhibitor has been found to block the actions of plasmin and the C'1r subcomponent of the first component of complement, and to retard the generation of PF/Dil. No inhibition of blood clotting or of the generation of plasmin was demonstrable.
摘要
已知人血清中被称为C'1酯酶抑制剂的部分可抑制C'1酯酶、血浆激肽释放酶以及血浆中一种增强皮肤血管通透性的酶PF/Dil的作用。在本研究中，已发现C'1酯酶抑制剂可阻断纤溶酶和补体第一成分的C'1r亚成分的作用，并延缓PF/Dil的产生。未证实其对血液凝固或纤溶酶生成有抑制作用。
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The inhibition of plasmin, plasma kallikrein, plasma permeability factor, and the C'1r subcomponent of the first component of complement by serum C'1 esterase inhibitor.血清C'1酯酶抑制剂对纤溶酶、血浆激肽释放酶、血浆通透因子及补体第一成分的C'1r亚成分的抑制作用。
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