果蝇光感受器中的光诱导电压噪声。
Light-induced voltage noise in the photoreceptor of Drosophila melanogaster.
作者信息
Wu C F, Pak W L
出版信息
J Gen Physiol. 1978 Mar;71(3):249-68. doi: 10.1085/jgp.71.3.249.
Abstract
The Drosophila photoreceptor potential is thought to be composed of discrete unit potentials called bumps. The steady-state receptor potential and the accompanying voltage fluctuations were recorded intracellularly under steady illumination. The occurrence rate, effective amplitude, and duration of the bumps were deduced by assuming a shot noise model. Over a wide range of light intensity, the duration of bumps remained essentially constant (25-30 ms). Below the saturation intensity for the receptor potential, the bump rate was roughly proportional to the intensity, and the adjustment of bumps to smaller size at higher intensity was mainly responsible for the nonlinear behavior of the receptor potential. The reduction in size of bumps at increasing light intensity was found to be due mainly to the diminishing magnitude of the bump current, and not to some other secondary effects. The bump rate saturated at about 3 x 105-106 events/s.
摘要
果蝇的光感受器电位被认为是由称为“脉冲”的离散单位电位组成。在稳定光照下，细胞内记录了稳态感受器电位和伴随的电压波动。通过假设散粒噪声模型推导了脉冲的发生率、有效幅度和持续时间。在很宽的光强度范围内，脉冲的持续时间基本保持恒定（25 - 30毫秒）。在感受器电位的饱和强度以下，脉冲频率大致与光强度成正比，并且在较高光强度下脉冲调整为较小尺寸主要是感受器电位非线性行为的原因。发现随着光强度增加脉冲尺寸减小主要是由于脉冲电流幅度减小，而不是其他一些次要效应。脉冲频率在约3×10⁵ - 10⁶次/秒时达到饱和。
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