Scott D, Beastall G
Q J Exp Physiol Cogn Med Sci. 1978 Apr;63(2):147-56. doi: 10.1113/expphysiol.1978.sp002427.
Adult sheep were given intravenous infusions of a solution of Na2HPO4 and the effects on parotid salivary composition and on plasma parathyroid hormone levels were studied. Infusion of the phosphate solution resulted in increases in the concentration of inorganic phosphate in the plasma and to proportional increases in the concentration and amount of phosphate secreted in the saliva. There was, however, no evidence that the salivary response was dependent upon a change in endogenous parathyroid hormone release. In other studies infusion of bovine parathyroid hormone or stimulation of endogenous hormone release through infusion of EDTA both led to a fall in the concentration of inorganic phosphate in the plasma and to a fall in the concentration and amount of phosphate secreted in the saliva. Taken together these results suggest that the major factor affecting salivary phosphate secretion in these studies was the concentration of inorganic phosphate in the plasma. Parathyroid hormone does not appear to have any direct effect on salivary phosphate secretion in the sheep though it may indirectly influence phosphate secretion through its effects on plasma inorganic phosphate level.
给成年绵羊静脉输注Na2HPO4溶液，并研究其对腮腺唾液成分和血浆甲状旁腺激素水平的影响。输注磷酸盐溶液导致血浆中无机磷酸盐浓度升高，唾液中分泌的磷酸盐浓度和量也相应增加。然而，没有证据表明唾液反应依赖于内源性甲状旁腺激素释放的变化。在其他研究中，输注牛甲状旁腺激素或通过输注EDTA刺激内源性激素释放，均导致血浆中无机磷酸盐浓度下降，唾液中分泌的磷酸盐浓度和量也下降。综合这些结果表明，在这些研究中影响唾液磷酸盐分泌的主要因素是血浆中无机磷酸盐的浓度。甲状旁腺激素似乎对绵羊唾液磷酸盐分泌没有直接影响，尽管它可能通过对血浆无机磷酸盐水平的影响间接影响磷酸盐分泌。
