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Relationship between the net electrical charge of antigens and specific antibodies. An example of selection by antigen of cells producing highest affinity antibody.

作者信息

Benacerraf B, Nussenzweig V, Maurer P H, Stylos W

出版信息

Isr J Med Sci. 1969 Mar-Apr;5(2):171-6.

PMID:4184816
Abstract
摘要

相似文献

1
Relationship between the net electrical charge of antigens and specific antibodies. An example of selection by antigen of cells producing highest affinity antibody.抗原的净电荷与特异性抗体之间的关系。抗原选择产生最高亲和力抗体的细胞的一个例子。
Isr J Med Sci. 1969 Mar-Apr;5(2):171-6.
2
Affinity and heterogeneity of antibodies induced by epsilon-2,4-dinitrophenylinsulin.ε-2,4-二硝基苯基胰岛素诱导产生的抗体的亲和力与异质性
Biochemistry. 1969 Jul;8(7):2729-36. doi: 10.1021/bi00835a006.
3
Dependence of the chemical nature of antibodies on the net electrical charge of antigens.抗体的化学性质对抗原净电荷的依赖性。
Proc Natl Acad Sci U S A. 1966 Feb;55(2):445-52. doi: 10.1073/pnas.55.2.445.
4
Lack of correlation between the net charge of antigen and antibodies in guinea pigs immunized with some charged antigens.在用某些带电荷抗原免疫的豚鼠中，抗原净电荷与抗体之间缺乏相关性。
J Immunol. 1971 Apr;106(4):1089-94.
5
[Biological and physico-chemical properties of specifically or non-specifically purified gamma-1 globulin from guinea pigs].[从豚鼠中特异性或非特异性纯化的γ-1球蛋白的生物学和物理化学性质]
Ann Inst Pasteur (Paris). 1968 Apr;114(4):474-89.
6
Studies on the immunogenicity of antigen-antibody precipitates. II. The suppressive effect of anti-carrier and anti-hapten antibodies on the immunogenicity of dinitrophenylated human gamma G globulin.抗原-抗体沉淀物的免疫原性研究。II. 抗载体抗体和抗半抗原抗体对二硝基苯基化人γG球蛋白免疫原性的抑制作用。
J Immunol. 1970 Jun;104(6):1540-9.
7
Secretory gamma-A antibodies induced by local immunization.局部免疫诱导产生的分泌型γ-A抗体。
Nature. 1969 Feb 15;221(5181):679-81. doi: 10.1038/221679a0.
8
Selective immunosuppression using antigens and antibodies as pharmacologic agents.使用抗原和抗体作为药物制剂的选择性免疫抑制。
Fed Proc. 1974 Aug;33(8):1886-8.
9
Antibody weight estimates at the nanogram level.抗体重量估计在纳克水平。
J Immunol. 1971 Jun;106(6):1507-18.
10
The synthesis and secretion of gamma-globulin by lymph node cells. V. The dissociation of the microsome-antibody complex with enzymatically and chemically altered gamma-globulins.淋巴结细胞对γ-球蛋白的合成与分泌。V. 微粒体-抗体复合物与经酶促和化学改变的γ-球蛋白的解离
J Biol Chem. 1969 Jan 25;244(2):440-8.

引用本文的文献

1
Flow-induced detachment of red blood cells adhering to surfaces by specific antigen-antibody bonds.血流诱导通过特异性抗原-抗体键黏附于表面的红细胞分离。
Biophys J. 1994 Apr;66(4):1222-30. doi: 10.1016/S0006-3495(94)80906-3.
2
Cellular aspects of the inverse relationship between the net charge of immunogens of antibodies elicited.所引发抗体的免疫原净电荷之间反比关系的细胞层面
Proc Natl Acad Sci U S A. 1970 Nov;67(3):1288-93. doi: 10.1073/pnas.67.3.1288.
3
Evidence for correlation between the antigenic specificity and charge of human IgG. A study of antibody-inducing lymphocyte mediated cell damage.
人类IgG抗原特异性与电荷之间相关性的证据。抗体诱导淋巴细胞介导的细胞损伤研究。
Immunology. 1972 Jun;22(6):1043-9.
4
Separation of normal and immune lymphoid cells by antigen-coated coated columns. Antigen-binding characteristics of membrane antibodies as analyzed by hapten-protein antigens.通过抗原包被柱分离正常和免疫淋巴细胞。通过半抗原-蛋白质抗原分析膜抗体的抗原结合特性。
J Exp Med. 1970 Jul 1;132(1):110-26. doi: 10.1084/jem.132.1.110.
5
The role of thymocytes and bone marrow cells in defining the response to the dinitrophenyl hapten attached to positively and negatively charged synthetic polypeptide carriers. Cell fractionation over charged columns.胸腺细胞和骨髓细胞在确定对附着于带正电和负电的合成多肽载体上的二硝基苯基半抗原的反应中的作用。在带电柱上进行细胞分级分离。
J Exp Med. 1973 Jan 1;137(1):183-95. doi: 10.1084/jem.137.1.183.
6
The sheep immune response. Variation of anti-hapten and anti-carrier antibodies in the 1 and 2 immunoglobulin fractions.绵羊免疫反应。1和2免疫球蛋白组分中抗半抗原和抗载体抗体的变化。
Immunology. 1973 May;24(5):781-9.
7
Unprimed spleen cell populations recognize macrophage-bound antigen with opposite net electric charge.未致敏的脾细胞群体识别带相反净电荷的巨噬细胞结合抗原。
Proc Natl Acad Sci U S A. 1977 Apr;74(4):1693-6. doi: 10.1073/pnas.74.4.1693.
8
Haptenic antibody induced by N-phthaloylated ox insulin in the Hartley guinea-pig.N-邻苯二甲酰化牛胰岛素在哈特利豚鼠体内诱导产生的半抗原抗体。
Clin Exp Immunol. 1978 Mar;31(3):464-71.
9
Inverse relationship between net electric charge on the antigen and that on the sensitized cell in cellular immune response: demonstration with basic encephalitogen of the brain.细胞免疫反应中抗原上的净电荷与致敏细胞上的净电荷之间的反比关系：用脑的碱性脑脊髓炎原进行的证明
J Exp Med. 1975 Sep 1;142(3):701-8. doi: 10.1084/jem.142.3.701.