原发性胆汁性肝硬化的免疫学和组织学研究。
Immunological and histological studies in primary biliary cirrhosis.
作者信息
Hadziyannis S, Scheuer P J, Feizi T, Naccarato R, Doniach D, Sherlock S
出版信息
J Clin Pathol. 1970 Mar;23(2):95-8. doi: 10.1136/jcp.23.2.95.
Abstract
Thirty-one patients with primary biliary cirrhosis in whom adequate histological liver material was available were studied by immunological and histological methods. There was no statistically significant correlation between individual histological features and the level of serum mitochondrial antibodies. A relationship between the duration of symptoms and histological stage of the disease supports the present concept of its evolution. However, several stages were often identified in the same specimen. Four cases with negative mitochondrial antibodies were similar to the other 27 clinically and histologically.
摘要
对31例有足够肝脏组织学材料的原发性胆汁性肝硬化患者采用免疫学和组织学方法进行了研究。单个组织学特征与血清线粒体抗体水平之间无统计学显著相关性。症状持续时间与疾病组织学分期之间的关系支持了目前关于其演变的概念。然而，在同一标本中常可发现几个阶段。4例线粒体抗体阴性的患者在临床和组织学上与其他27例相似。
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