在e基因（噬菌体溶菌酶）中存在缺失且对T4噬菌体敏感的大肠杆菌突变体。
Escherichia coli mutants permissive for T4 bacteriophage with deletion in e gene (phage lysozyme).
作者信息
Sundar Raj C V, Wu H C
出版信息
J Bacteriol. 1973 May;114(2):656-65. doi: 10.1128/jb.114.2.656-665.1973.
Abstract
Escherichia coli mutants have been isolated that are permissive for the infection by T4 phage with deletion in the cistron for the phage lysozyme, the e gene. Some, but not all, of these mutants are simultaneously permissive for the infection by T4 phage defective in the t gene, the product of which has also been implicated in the release of progeny phages. Most of these mutants shared the following properties: temperature sensitivity in growth and cell division, increased sensitivity towards a number of unrelated antibiotics and colicins, and increased sensitivity towards anionic detergents (sodium dodecyl sulfate and sodium deoxycholate). The possible biochemical basis for these phenotypes is discussed.
摘要
已经分离出大肠杆菌突变体，这些突变体允许T4噬菌体感染，该噬菌体在噬菌体溶菌酶的顺反子（即e基因）中存在缺失。其中一些（但不是全部）突变体同时允许t基因缺陷的T4噬菌体感染，t基因的产物也与子代噬菌体的释放有关。这些突变体中的大多数具有以下共同特性：生长和细胞分裂中的温度敏感性、对多种不相关抗生素和大肠杆菌素的敏感性增加，以及对阴离子去污剂（十二烷基硫酸钠和脱氧胆酸钠）的敏感性增加。文中讨论了这些表型可能的生化基础。
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