麻疹对尼日利亚儿童免疫反应的影响。
Effects of measles on the immune response of Nigerian children.
作者信息
Whittle H C, Bradley-Moore A, Fleming A, Greenwood B M
出版信息
Arch Dis Child. 1973 Oct;48(10):753-6. doi: 10.1136/adc.48.10.753.
Abstract
The effects of measles on the immune system of Nigerian children were investigated. At the time of the rash, skin tests to tuberculin purified protein derivative, candida, and streptococcal antigens were negative. Skin sensitization with dinitrochlorobenzene and lymphocyte transformation by phytohaemagglutinin were normal. Antibody response to the H and O antigens of was deficient. Established humoral response and serum immunoglobulin levels were normal. Immunosuppression induced by the measles virus, sometimes acting synergistically with immunosuppression due to malnutrition, may contribute to the high prevalence of serious complications seen after measles in tropical developing countries.
摘要
对尼日利亚儿童麻疹对免疫系统的影响进行了调查。出疹时，对结核菌素纯蛋白衍生物、念珠菌和链球菌抗原的皮肤试验呈阴性。用二硝基氯苯进行皮肤致敏和用植物血凝素进行淋巴细胞转化均正常。对[具体病原体]的H和O抗原的抗体反应不足。已建立的体液反应和血清免疫球蛋白水平正常。麻疹病毒诱导的免疫抑制，有时与营养不良导致的免疫抑制协同作用，可能是热带发展中国家麻疹后严重并发症高发的原因之一。 （原文中“对 的H和O抗原”这里缺少具体病原体信息）
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本文引用的文献
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ANTIGENIC STIMULATION IN UNDERNOURISHED CHILDREN.营养不良儿童的抗原刺激
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EFFECTS OF MEASLES, GAMMA-GLOBULIN-MODIFIED MEASLES AND VACCINE MEASLES ON THE TUBERCULIN TEST.麻疹、丙种球蛋白改良麻疹及麻疹疫苗对结核菌素试验的影响
N Engl J Med. 1964 Feb 20;270:386-91. doi: 10.1056/NEJM196402202700802.
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Importance of measles to India.麻疹对印度的重要性。
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Measles epidemics in Greenland.格陵兰的麻疹疫情。
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Measles in West Africa.西非的麻疹
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Severe measles in the tropics. I.热带地区的严重麻疹。一、
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