唇癌的危险因素：基于流行病学比较的批判性评估。
Risk factors of lip cancer: a critical evaluation based on epidemiological comparisons.
作者信息
Lindqvist C
出版信息
Am J Public Health. 1979 Mar;69(3):256-60. doi: 10.2105/ajph.69.3.256.
A description is given of the occurrence of lip, skin, and intraoral cancers in Finland in the period 1953-1973 with the aim of testing certain etiologic hypotheses. In addition, data on lip cancer were correlated with those of some other types of cancer. Substantial differences with respect to various epidemiologic parameters were found between lip and skin cancers. However, there were similarities between lip cancer and cancers of the upper gastrointestinal canal and respiratory organs (especially lung cancer). Negative geographic correlation was found between the age-adjusted incidence rate of lip cancer and that of cancers of the colon and prostate. In addition, the correlation was highly negative for the median income per capita (p less than 0.001). It was concluded that, in terms of cancer etiology, lip cancer is more closely related to cancer of the oral cavity than to that of the skin. Moreover, some specific socioeconomic factors associated with a low standard of living must be considered as noteworthy risk factors of lip cancer.
本文描述了1953年至1973年芬兰唇癌、皮肤癌和口腔内癌的发病情况，旨在检验某些病因假说。此外，还将唇癌数据与其他几种癌症的数据进行了关联分析。结果发现，唇癌和皮肤癌在各种流行病学参数方面存在显著差异。然而，唇癌与上消化道癌和呼吸器官癌（尤其是肺癌）之间存在相似之处。唇癌的年龄调整发病率与结肠癌和前列腺癌的年龄调整发病率之间存在负地理相关性。此外，与人均收入中位数的相关性也呈高度负相关（p<0.001）。研究得出结论，从癌症病因学角度来看，唇癌与口腔癌的关系比与皮肤癌的关系更为密切。此外，一些与低生活水平相关的特定社会经济因素必须被视为唇癌值得关注的危险因素。
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