Abrams R, Taylor M A, Coleman Stolurow K A
Biol Psychiatry. 1979 Feb;14(1):111-7.
We performed a factor analysis on research data from 55 consecutive hospitalized psychiatric patients who showed one or more of eight catatonic motor features. Two factors were extracted, accounting for 32% of the variance. Factor 1 (mutism, negativism, stupor) corresponded to the clinical syndrome of negativistic stupor and was unrelated to diagnosis, sex, age at onset, family history, or treatment response. Factor 2 (mutism, stereotypy, catalepsy, automatic obedience) corresponded to the classical description of catatonia, was associated with a research diagnosis of mania, and tended (p less than 0.10) to predict a favorable treatment response. We suggest that the two factors may reflect different forms of cerebral dysfunction which, in the case of Factor 2, may provide clues as to the nature of the morbid process in mania. Republication is now in progress in a different sample.
我们对55例连续住院的精神病患者的研究数据进行了因子分析，这些患者表现出八种紧张性运动特征中的一种或多种。提取了两个因子，解释了32%的方差。因子1（缄默、违拗、木僵）对应于违拗性木僵的临床综合征，与诊断、性别、起病年龄、家族史或治疗反应无关。因子2（缄默、刻板动作、蜡样屈曲、自动服从）对应于紧张症的经典描述，与躁狂症的研究诊断相关，并且倾向于（p小于0.10）预测良好的治疗反应。我们认为这两个因子可能反映了不同形式的脑功能障碍，就因子2而言，可能为躁狂症发病过程的本质提供线索。目前正在不同样本中进行重新发表。
