van der Kaay H J, Klein F, Hagenaar-de Weerdt M, Meuwissen J H
Bull World Health Organ. 1973;49(3):267-74.
An investigation of malariometric indices in relation to immunoglobulin levels, rheumatoid factors, and antithyroglobulins was carried out on 78 members of the Arfak tribe near Manokwari in Western New Guinea, in the course of a WHO assessment of malaria control activities in that region. The population investigated had been exposed to a period of epidemic malaria, as indicated by the small differences in malariometric indices between consecutive age groups. Typically high spleen sizes were recorded, as found generally among Papuans in similar situations. Falciparum malaria was most prevalent, almost equal to cases of vivax and malariae malaria together. IgM levels were very high, while those of IgG, IgA and IgD were not elevated. Total serum protein was rather low. No correlation between malariometric indices, autoantibodies, and immunoglobulin levels could be found. In particular there was no correlation between IgM levels and spleen indices, such as has been found in many other surveys. It is suggested that splenomegaly may show no correlation with the IgM level in Papuan populations without previous selection.
在世界卫生组织对新几内亚西部马诺夸里附近的阿尔法克部落78名成员进行该地区疟疾控制活动评估期间，开展了一项关于疟疾测量指标与免疫球蛋白水平、类风湿因子及抗甲状腺球蛋白之间关系的调查。连续年龄组之间疟疾测量指标差异较小，表明被调查人群经历过一段疟疾流行期。记录到脾脏肿大情况通常较高，这在巴布亚人处于类似情况时普遍存在。恶性疟最为流行，几乎与间日疟和三日疟病例总数相当。IgM水平非常高，而IgG、IgA和IgD水平未升高。血清总蛋白较低。未发现疟疾测量指标、自身抗体和免疫球蛋白水平之间存在相关性。特别是在IgM水平与脾脏指标之间未发现相关性，而这在许多其他调查中都有发现。研究表明，在未经预先筛选的巴布亚人群中，脾肿大可能与IgM水平无关。
