一种影响新月柄杆菌极性发育事件表达的多效性突变。

Kurn N, Ammer S, Shapiro L

Proc Natl Acad Sci U S A. 1974 Aug;71(8):3157-61. doi: 10.1073/pnas.71.8.3157.

A developmental mutant of C. crescentus with altered polar surface structures has been isolated. The mutant lacks a flagellum and pili, and may have an abnormal DNA phage receptor site. A revertant regains the normal structures simultaneously. This point mutation allows normal flagellin synthesis, stalk formation, equatorial cell division, and rate of growth. The mutant phenotype indicates that the assembly of the polar surface structures is coordinately regulated and independent of mechanisms regulating cell polarity and division.

已分离出一种新月柄杆菌的发育突变体，其极性表面结构发生了改变。该突变体缺乏鞭毛和菌毛，可能具有异常的DNA噬菌体受体位点。回复突变体同时恢复了正常结构。这种点突变允许正常的鞭毛蛋白合成、柄形成、赤道细胞分裂和生长速率。突变体表型表明极性表面结构的组装受到协调调节，并且独立于调节细胞极性和分裂的机制。