6-（对）-羟基苯基偶氮尿嘧啶诱导枯草芽孢杆菌中的原噬菌体SPO2
Induction of prophage SPO2 in Bacillus subtilis by 6-(para)-hydroxyphenylazouracil.
作者信息
Arwert F, Rutberg L
出版信息
J Virol. 1974 Dec;14(6):1470-5. doi: 10.1128/JVI.14.6.1470-1475.1974.
Abstract
DNA replication in Bacillus subtilis is reversibly inhibited by 6-(para)-hydroxyphenylazouracil (HpUra) (1971), whereas replication of temperature phage SPO2 is not affected by the drug. Experiments are presented which show that HpUra will induce bacteria lysogenic for SPO2. Also, prophage phi105, which is sensitive to the drug, is induced by HpUra. Induction of SPO2 lysogenics in the presence of HpUra gives selective synthesis of SPO2 DNA.
摘要
枯草芽孢杆菌中的DNA复制会被6-（对）-羟基苯偶氮尿嘧啶（HpUra）可逆性抑制（1971年），而温度噬菌体SPO2的复制不受该药物影响。本文展示的实验表明，HpUra会诱导携带SPO2的溶原菌。此外，对该药物敏感的原噬菌体phi105也会被HpUra诱导。在存在HpUra的情况下诱导携带SPO2的溶原菌会选择性合成SPO2 DNA。
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