Fields P I, Yasbin R E
J Bacteriol. 1980 Oct;144(1):473-5. doi: 10.1128/jb.144.1.473-475.1980.
6-(p-Hydroxyphenylazo)-uracil, a purine analog that is known to specifically inhibit deoxyribonucleic acid polymerase III in gram-positive organisms, inhibited W-reactivation in Bacillus subtilis. On the other hand, W-reactivation proceeded normally in the presence of 6-(p-hydroxyphenylazo)-uracil when a strain possessing a resistant deoxyribonucleic acid polymerase III was used as the host.
6-(对羟基苯偶氮)尿嘧啶是一种嘌呤类似物,已知其能特异性抑制革兰氏阳性菌中的脱氧核糖核酸聚合酶III,它抑制了枯草芽孢杆菌中的W复活。另一方面,当使用具有抗性脱氧核糖核酸聚合酶III的菌株作为宿主时,在6-(对羟基苯偶氮)尿嘧啶存在的情况下,W复活正常进行。