蟾蜍和蛙卵母细胞发育过程中的细胞内钠和钾浓度
Intracellular sodium and potassium concentrations in toad and frog oocytes during development.
作者信息
Cannon J D, Dick D A, Ho-Yen D O
出版信息
J Physiol. 1974 Sep;241(2):497-508. doi: 10.1113/jphysiol.1974.sp010668.
Abstract
- During growth of oocytes of Bufo bufo from approximately 700-2000 mum in diameter, intracellular Na rose from 20 to 120 m-mole/l. cell water while K fell from 120 to 15 m-mole/l. cell water.2. In Rana temporaria Na similarly rose from 9 to 190 m-mole/l. cell water and K fell from 126 to 28 m-mole/l. cell water.3. At the same time in both Bufo and Rana the ouabain-sensitive Na efflux, the ouabain-insensitive Na efflux, and the total Na influx all increased.4. It is concluded that the predominant process is an increase of passive Na permeability. The increase of apparently active Na efflux may be secondary to the consequent rise in intracellular Na.
摘要
- 在中华大蟾蜍卵母细胞从直径约700 - 2000微米生长过程中，细胞内钠离子浓度从20毫摩尔/升细胞内水升至120毫摩尔/升细胞内水，而钾离子浓度从120毫摩尔/升细胞内水降至15毫摩尔/升细胞内水。2. 在林蛙中，钠离子浓度同样从9毫摩尔/升细胞内水升至190毫摩尔/升细胞内水，钾离子浓度从126毫摩尔/升细胞内水降至28毫摩尔/升细胞内水。3. 同时，在中华大蟾蜍和林蛙中，哇巴因敏感的钠外流、哇巴因不敏感的钠外流以及总钠内流均增加。4. 得出的结论是，主要过程是被动钠通透性增加。明显的主动钠外流增加可能是细胞内钠离子浓度随之升高的继发结果。
相似文献
1
Intracellular sodium and potassium concentrations in toad and frog oocytes during development.
J Physiol. 1974 Sep;241(2):497-508. doi: 10.1113/jphysiol.1974.sp010668.
2
Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation.
J Physiol. 1974 Sep;241(2):509-14. doi: 10.1113/jphysiol.1974.sp010669.
3
Sodium fluxes in single amphibian oocytes: further studies and a new model.
J Physiol. 1975 May;247(1):91-116. doi: 10.1113/jphysiol.1975.sp010922.
4
The effect of ouabain on 22-Na influx and 42-K efflux in amphibian oocytes.
J Physiol. 1975 Jan;244(1):37P-38P.
5
The ouabain-sensitive fluxes of sodium and potassium in squid giant axons.
J Physiol. 1969 Feb;200(2):459-96. doi: 10.1113/jphysiol.1969.sp008703.
6
Proceedings: The effect of ouabain, low temperature and exposure to Li solutions on cation fluxes in amphibian oocytes.
J Physiol. 1974 Apr;238(1):71P-72P.
7
Effect of prolonged ouabain treatment of Na, K, Cl and Ca concentration and fluxes in cultured human cells.
J Physiol. 1972 Sep;225(3):599-617. doi: 10.1113/jphysiol.1972.sp009959.
8
Effect of ouabain and metabolic inhibitors on the Na and K movements and nucleotide contents of L cells.
J Physiol. 1971 Mar;213(3):665-82. doi: 10.1113/jphysiol.1971.sp009407.
9
A new model for Na fluxes in amphibian oocytes.
J Physiol. 1972 Sep;225(2):22P-25P.
10
Partition of sodium fluxes in isolated toad oocytes.
J Physiol. 1967 Jul;191(2):289-308. doi: 10.1113/jphysiol.1967.sp008251.
引用本文的文献
1
Elevated intracellular Na concentrations in developing spinal neurons.
J Neurochem. 2017 Mar;140(5):755-765. doi: 10.1111/jnc.13936. Epub 2017 Jan 23.
2
Exaggerated hyperkalaemia in acute myeloid leukaemia.
Br Med J (Clin Res Ed). 1981 Apr 18;282(6272):1323-4. doi: 10.1136/bmj.282.6272.1323-d.
3
The distribution of small ions during the early development of Xenopus laevis and Ambystoma mexicanum embryos.
J Physiol. 1983 Nov;344:359-77. doi: 10.1113/jphysiol.1983.sp014945.
4
Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation.
J Physiol. 1974 Sep;241(2):509-14. doi: 10.1113/jphysiol.1974.sp010669.
5
A possible mechanism for concentrating sodium and potassium in the cell nucleus.
Biophys J. 1976 May;16(5):527-33. doi: 10.1016/S0006-3495(76)85707-4.
6
Proceedings: Binding to nerve and muscle of saxitoxin labelled by a new method of tritium exchange.
J Physiol. 1976 Jun;258(2):99P-100P.
7
Sodium fluxes in single amphibian oocytes: further studies and a new model.
J Physiol. 1975 May;247(1):91-116. doi: 10.1113/jphysiol.1975.sp010922.
8
Activity coefficients of intracellular Na+ and K+ during development of frog oocytes.
J Membr Biol. 1978 Apr 20;40(1):25-38. doi: 10.1007/BF01909737.
9
The distribution of sodium, potassium and chloride in the nucleus and cytoplasm of Bufo bufo oocytes measured by electron microprobe analysis.
J Physiol. 1978 Nov;284:37-53. doi: 10.1113/jphysiol.1978.sp012526.
本文引用的文献
1
NA FLUXES IN SINGLE TOAD OOCYTES WITH SPECIAL REFERENCE TO THE EFFECT OF EXTERNAL AND INTERNAL NA CONCENTRATION ON NA EFFLUX.
J Physiol. 1964 Oct;174(1):55-90. doi: 10.1113/jphysiol.1964.sp007474.
2
Sodium and potassium in oocytes of Triturus cristatus.
J Cell Sci. 1969 Mar;4(2):299-304. doi: 10.1242/jcs.4.2.299.
3
The action of ethacrynic acid on sodium efflux from single toad oocytes.
J Physiol. 1968 Jun;196(3):693-701. doi: 10.1113/jphysiol.1968.sp008530.
4
Autoradiographic demonstration of inhomogeneous distribution of sodium in single oocytes of Bufo bufo.
J Physiol. 1970 Sep;210(2):305-19. doi: 10.1113/jphysiol.1970.sp009212.
5
The concentrations of water, sodium and potassium in the nucleus and cytoplasm of amphibian oocytes.
J Cell Sci. 1970 Jul;7(1):5-13. doi: 10.1242/jcs.7.1.5.
6
The effect of surface microvilli on the water permeability of single toad oocytes.
J Cell Sci. 1970 Mar;6(2):451-76. doi: 10.1242/jcs.6.2.451.
7
Uptake of ( 3 H)ouabain and Na pump turnover rates in cells cultured in ouabain.
J Physiol. 1972 Sep;225(3):619-35. doi: 10.1113/jphysiol.1972.sp009960.
8
The distribution of sodium and potassium in amphibian embryos during early development.
J Physiol. 1973 Jul;232(2):297-312. doi: 10.1113/jphysiol.1973.sp010271.
9
Intracellular sodium and potassium concentrations in oocytes of Bufo bufo at the beginning of maturation.
J Physiol. 1974 Sep;241(2):509-14. doi: 10.1113/jphysiol.1974.sp010669.
Zotero 插件