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During growth of oocytes of Bufo bufo from approximately 700-2000 mum in diameter, intracellular Na rose from 20 to 120 m-mole/l. cell water while K fell from 120 to 15 m-mole/l. cell water.2. In Rana temporaria Na similarly rose from 9 to 190 m-mole/l. cell water and K fell from 126 to 28 m-mole/l. cell water.3. At the same time in both Bufo and Rana the ouabain-sensitive Na efflux, the ouabain-insensitive Na efflux, and the total Na influx all increased.4. It is concluded that the predominant process is an increase of passive Na permeability. The increase of apparently active Na efflux may be secondary to the consequent rise in intracellular Na.

在中华大蟾蜍卵母细胞从直径约700 - 2000微米生长过程中，细胞内钠离子浓度从20毫摩尔/升细胞内水升至120毫摩尔/升细胞内水，而钾离子浓度从120毫摩尔/升细胞内水降至15毫摩尔/升细胞内水。2. 在林蛙中，钠离子浓度同样从9毫摩尔/升细胞内水升至190毫摩尔/升细胞内水，钾离子浓度从126毫摩尔/升细胞内水降至28毫摩尔/升细胞内水。3. 同时，在中华大蟾蜍和林蛙中，哇巴因敏感的钠外流、哇巴因不敏感的钠外流以及总钠内流均增加。4. 得出的结论是，主要过程是被动钠通透性增加。明显的主动钠外流增加可能是细胞内钠离子浓度随之升高的继发结果。

During growth of oocytes of Bufo bufo from approximately 700-2000 mum in diameter, intracellular Na rose from 20 to 120 m-mole/l. cell water while K fell from 120 to 15 m-mole/l. cell water.2. In Rana temporaria Na similarly rose from 9 to 190 m-mole/l. cell water and K fell from 126 to 28 m-mole/l. cell water.3. At the same time in both Bufo and Rana the ouabain-sensitive Na efflux, the ouabain-insensitive Na efflux, and the total Na influx all increased.4. It is concluded that the predominant process is an increase of passive Na permeability. The increase of apparently active Na efflux may be secondary to the consequent rise in intracellular Na.

在中华大蟾蜍卵母细胞从直径约700 - 2000微米生长过程中，细胞内钠离子浓度从20毫摩尔/升细胞内水升至120毫摩尔/升细胞内水，而钾离子浓度从120毫摩尔/升细胞内水降至15毫摩尔/升细胞内水。2. 在林蛙中，钠离子浓度同样从9毫摩尔/升细胞内水升至190毫摩尔/升细胞内水，钾离子浓度从126毫摩尔/升细胞内水降至28毫摩尔/升细胞内水。3. 同时，在中华大蟾蜍和林蛙中，哇巴因敏感的钠外流、哇巴因不敏感的钠外流以及总钠内流均增加。4. 得出的结论是，主要过程是被动钠通透性增加。明显的主动钠外流增加可能是细胞内钠离子浓度随之升高的继发结果。

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