Stumpa A, Cihla F, Tůmová B, Husek V, Slezácek J
Acta Virol. 1979 Sep;23(5):443-5.
A group of 35 adolescents aged 18--22 years were vaccinated intradermally with 0.2 ml of a mixed A (H3N2) + A (Hsw1N1) formolized vaccine and revaccinated with A (Hsw1N1) monovaccine 10 days before an A (H1N1) influenza epidemic. The vaccination had no effect on morbidity or the clinical course of disease. Serology revealed a primary immune response to A (Hsw1N1) and a booster response to A (H3N2). Apparently, prevention of a new influenza subtype by formolized vaccine possessing only the corresponding neuraminidase type is ineffective.
一组35名年龄在18至22岁的青少年在A（H1N1）流感流行前10天，皮内注射0.2毫升混合的A（H3N2）+ A（Hsw1N1）甲醛化疫苗，并再次接种A（Hsw1N1）单价疫苗。接种疫苗对发病率或疾病的临床病程没有影响。血清学检测显示对A（Hsw1N1）有初次免疫反应，对A（H3N2）有加强反应。显然，仅拥有相应神经氨酸酶类型的甲醛化疫苗预防新型流感亚型是无效的。
