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[近期脑梗死患者血液和脑脊液中的色氨酸和酪氨酸]

[Tryptophan and tyrosine in blood and cerebrospinal fluid in patients with recent cerebral infarct].

作者信息

Stelmasiak Z

出版信息

Neurol Neurochir Pol. 1979 Jan-Feb;13(1):1-6.

PMID:424044
Abstract

The determinations were carried out in the blood and cerebrospinal fluid of 40 patients with recent cerebral infarction and 30 controls. Tryptophan concentration was determined by the fluorimetric method of Denckla and Dewey, and tyrosine concentration by the method of Waalkes and Udenfried. A statistically significant rise of free tryptophan concentration in the plasma and tryptophan concentration in the cerebrospinal fluid was found which seemed to depend on the stress reaction following brain infarction. No statistically significant changes were observed in the concentration of tyrosine in the cerebrospinal fluid and plasma in patients with brain infarction.

摘要

对40例近期脑梗死患者及30例对照者的血液和脑脊液进行了检测。采用丹克拉和杜威的荧光法测定色氨酸浓度,采用瓦尔克斯和乌登弗里德的方法测定酪氨酸浓度。发现血浆中游离色氨酸浓度及脑脊液中色氨酸浓度有统计学意义的升高,这似乎取决于脑梗死后的应激反应。脑梗死患者脑脊液和血浆中酪氨酸浓度未观察到有统计学意义的变化。

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