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3
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本文引用的文献

1
Production of Antibody in Mammary Gland of Pregnant, Non-Lactating and Lactating Cows, Evoked by Polyvalent Antigen with Reference to Dosage and Frequency of Immunization.关于免疫剂量和频率,多价抗原诱发怀孕、非泌乳和泌乳奶牛乳腺产生抗体的研究
Can J Comp Med Vet Sci. 1964 Aug;28(8):183-92.
2
THE IMMUNE RESPONSE OF THE MAMMARY GLAND AND REGIONAL LYMPH NODE FOLLOWING ANTIGENIC STIMULATION.抗原刺激后乳腺和区域淋巴结的免疫反应。
Aust J Exp Biol Med Sci. 1965 Jun;43:265-74. doi: 10.1038/icb.1965.25.
3
[Preliminary research on the obtention of antibodies of the aftosa fever virus in cow's milk after injection of virus into the teat duct (diathelic immunization)].[经乳管注射病毒后在牛奶中获取口蹄疫病毒抗体的初步研究(经乳免疫)]
C R Hebd Seances Acad Sci. 1961 Mar 13;252:1690-2.
4
Studies relating to the formation of neutralizing antibody following the propagation of influenza and Newcastle disease virus in the bovine mammary gland.关于流感病毒和新城疫病毒在牛乳腺中繁殖后中和抗体形成的研究。
Can J Microbiol. 1956 May;2(3):322-8. doi: 10.1139/m56-037.
5
Antibody production in milk serum after virus instillation of goat mammary gland. II. Biochemical isolation and purification of antibody to influenza virus.山羊乳腺接种病毒后乳清中的抗体产生。II. 流感病毒抗体的生化分离与纯化。
Can J Microbiol. 1967 Sep;13(9):1195-201. doi: 10.1139/m67-164.
6
Antibody production in milk serum after virus instillation of goat mammary gland. I. Responses to influenza virus, mumps virus, and adenovirus 3.山羊乳腺接种病毒后乳清中的抗体产生。I. 对流感病毒、腮腺炎病毒和腺病毒3的反应。
Can J Microbiol. 1967 Aug;13(8):1069-78. doi: 10.1139/m67-143.
7
Local production of antibody by the lactating mammary gland following antigenic stimulation.抗原刺激后,泌乳乳腺的局部抗体产生。
Aust J Exp Biol Med Sci. 1966 Apr;44(2):169-80. doi: 10.1038/icb.1966.18.
8
A study of procine enteroviruses isolated from swine in the Toronto area. I. Isolation and serological grouping of viruses.对从多伦多地区猪只中分离出的猪肠道病毒的研究。I. 病毒的分离和血清学分组
Can J Comp Med Vet Sci. 1966 Nov;30(11):308-10.
9
Transmissible gastroenteritis of swine in Ontario.安大略省猪的传染性胃肠炎
Can J Comp Med. 1969 Jan;33(1):59-63.
10
A viral gastroenteritis of Ontario swine. 1. Clinical illness and recovery of the virus.安大略省猪的病毒性肠胃炎。1. 临床病症与病毒的恢复情况
Can J Comp Med Vet Sci. 1967 Aug;31(8):193-6.

用细胞培养的猪传染性胃肠炎病毒对母猪进行实验性免疫接种。

Experimental immunization of sows with cell-cultured TGE virus.

作者信息

Thorsen J, Djurickovic S

出版信息

Can J Comp Med. 1970 Jul;34(3):177-80.

PMID:4248437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1319489/
Abstract

Five sows were inoculated with a cell-cultured, cytopathic strain of the virus of transmissible gastroenteritis (TGE). Two sows were inoculated intramuscularly, and three by the intramammary route. The response was measured by the neutralizing antibody titers in the serum and the milk, and by the protection against experimental challenge of piglets nursing the sows. There were no marked differences in the serum or milk antibody titers resulting after the two methods of inoculation, although milk titers at the time of challenge were higher after intramammary inoculation. Piglets nursing sows inoculated by the intramammary route were protected to a greater extent than those nursing sows inoculated intramuscularly.

摘要

五头母猪接种了细胞培养的、具有细胞病变效应的传染性胃肠炎(TGE)病毒株。两头母猪通过肌肉注射接种,三头通过乳腺途径接种。通过血清和乳汁中的中和抗体滴度以及对哺乳母猪所产仔猪进行实验性攻毒的保护情况来衡量反应。两种接种方法后血清或乳汁抗体滴度没有显著差异,尽管在攻毒时乳腺接种后的乳汁滴度更高。通过乳腺途径接种的母猪所哺乳的仔猪比肌肉注射接种的母猪所哺乳的仔猪受到了更大程度的保护。