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Experimental immunization of sows with inactivated transmissible gastroenteritis (TGE) virus.

作者信息

Thorsen J, Djurickovic S

出版信息

Can J Comp Med. 1971 Apr;35(2):99-102.

PMID:4253469
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1319556/
Abstract

Four sows were immunized with inactivated TGE virus. The virus was either propagated in pig kidney cell cultures, or obtained from the intestines of experimentally infected gnotobiotic pigs, and inactivated by treatment with beta-propiolactone. The inactivated virus preparations were administered to sows by intramammary inoculation. Two sows received two inoculations; the other two sows received three inoculations of inactivated virus. The antibody responses in the serum and milk were determined and piglets nursing the sows were experimentally challenged with virulent TGE virus. Three inoculations of the virus preparation stimulated much higher levels of serum and milk antibody than did two inoculations. A schedule of three inoculations of sows with inactivated TGE virus was effective in stimulating protection against TGE for piglets nursing these sows.

摘要

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本文引用的文献

1
Experimental immunisation of sows against transmissible gastroenteritis. I. Immunisation with a bacteria-free suspension of transmissible gastroenteritis virus prepared from the intestines of infected pigs.母猪抗传染性胃肠炎的实验性免疫。I. 用从感染猪肠道制备的传染性胃肠炎病毒无菌悬液进行免疫。
Vet Rec. 1970 Jul 18;87(3):62-4. doi: 10.1136/vr.87.3.62.
2
A study of procine enteroviruses isolated from swine in the Toronto area. I. Isolation and serological grouping of viruses.对从多伦多地区猪只中分离出的猪肠道病毒的研究。I. 病毒的分离和血清学分组
Can J Comp Med Vet Sci. 1966 Nov;30(11):308-10.
3
Experimental immunization of sows with cell-cultured TGE virus.用细胞培养的猪传染性胃肠炎病毒对母猪进行实验性免疫接种。
Can J Comp Med. 1970 Jul;34(3):177-80.

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