Goering R V, Pattee P A
J Bacteriol. 1971 Apr;106(1):157-61. doi: 10.1128/jb.106.1.157-161.1971.
Nitrosoguanidine (NG) mutagenesis of Staphylococcus aureus resulted in the isolation of eight mutants exhibiting 3 to 28 times greater sensitivity to ultraviolet (UV) radiation. These mutants were further characterized by their ability to repair UV-irradiated bacteriophage, to act as recipients in the transduction of antibiotic resistance, and their sensitivity to NG. Based on the available data, six of these mutants are reduced in their ability to perform host-cell reactivation. One of the remaining two mutants may be deficient in post-replication repair.
用亚硝基胍（NG）对金黄色葡萄球菌进行诱变，结果分离出8个对紫外线（UV）辐射敏感程度高3至28倍的突变体。这些突变体通过其修复紫外线照射噬菌体的能力、作为抗生素抗性转导受体的能力以及对NG的敏感性进一步表征。根据现有数据，其中6个突变体进行宿主细胞复活的能力降低。其余两个突变体中的一个可能在复制后修复方面存在缺陷。
