对紫外线辐射敏感性增加的金黄色葡萄球菌突变体。
Mutants of Staphylococcus aureus with increased sensitivity to ultraviolet radiation.
作者信息
Goering R V, Pattee P A
出版信息
J Bacteriol. 1971 Apr;106(1):157-61. doi: 10.1128/jb.106.1.157-161.1971.
Abstract
Nitrosoguanidine (NG) mutagenesis of Staphylococcus aureus resulted in the isolation of eight mutants exhibiting 3 to 28 times greater sensitivity to ultraviolet (UV) radiation. These mutants were further characterized by their ability to repair UV-irradiated bacteriophage, to act as recipients in the transduction of antibiotic resistance, and their sensitivity to NG. Based on the available data, six of these mutants are reduced in their ability to perform host-cell reactivation. One of the remaining two mutants may be deficient in post-replication repair.
摘要
用亚硝基胍（NG）对金黄色葡萄球菌进行诱变，结果分离出8个对紫外线（UV）辐射敏感程度高3至28倍的突变体。这些突变体通过其修复紫外线照射噬菌体的能力、作为抗生素抗性转导受体的能力以及对NG的敏感性进一步表征。根据现有数据，其中6个突变体进行宿主细胞复活的能力降低。其余两个突变体中的一个可能在复制后修复方面存在缺陷。
相似文献
1
Mutants of Staphylococcus aureus with increased sensitivity to ultraviolet radiation.对紫外线辐射敏感性增加的金黄色葡萄球菌突变体。
J Bacteriol. 1971 Apr;106(1):157-61. doi: 10.1128/jb.106.1.157-161.1971.
2
Isolation of the rec mutants in Staphylococcus aureus.金黄色葡萄球菌中rec突变体的分离
J Bacteriol. 1972 Dec;112(3):1169-76. doi: 10.1128/jb.112.3.1169-1176.1972.
3
Mutants of Staphylococcus aureus deficient in recombinational repair. Improved isolation by selecting for mutants exhibiting concurrent sensitivity to ultraviolet radiation and N-methyl-N'-nitro-N-nitrosoguanidine.重组修复缺陷的金黄色葡萄球菌突变体。通过选择对紫外线辐射和N-甲基-N'-硝基-N-亚硝基胍同时敏感的突变体来改进分离方法。
Mutat Res. 1979 May;60(3):279-89. doi: 10.1016/0027-5107(79)90018-6.
4
Induction of mutants of Staphylococcus aureus 100 with increased ability to produce enterotoxin A.诱导金黄色葡萄球菌100产生肠毒素A能力增强的突变体。
J Bacteriol. 1971 Apr;106(1):289-91. doi: 10.1128/jb.106.1.289-291.1971.
5
Genetic control of chromosomal and plasmid recombination in Staphylococcus aureus.金黄色葡萄球菌中染色体和质粒重组的遗传控制。
Genetics. 1974 Apr;76(4):681-702. doi: 10.1093/genetics/76.4.681.
6
Penicillinase plasmids of Staphylococcus aureus.金黄色葡萄球菌的青霉素酶质粒
Fed Proc. 1967 Jan-Feb;26(1):29-38.
7
Transfer of tetracycline-resistance between strains of Staphylococcus aureus in mixed cultures.金黄色葡萄球菌菌株在混合培养物中四环素抗性的转移。
J Gen Microbiol. 1971 Dec;69(2):229-37. doi: 10.1099/00221287-69-2-229.
8
Effects of the recipient strain and ultraviolet irradiation on transduction kinetics of the penicillinase plasmid of Staphylococcus aureus.受体菌株和紫外线照射对金黄色葡萄球菌青霉素酶质粒转导动力学的影响。
J Bacteriol. 1971 Dec;108(3):1192-9. doi: 10.1128/jb.108.3.1192-1199.1971.
9
The action of nitrosoguanidine and other DNA-inactivating agents on Streptococcus pyogenes K56 strains with normal and reduced dark repair ability.亚硝基胍及其他DNA灭活剂对具有正常和降低的暗修复能力的化脓性链球菌K56菌株的作用。
Mol Gen Genet. 1968;102(3):241-6. doi: 10.1007/BF00385980.
10
Deoxyribonuclease production in populations of staphylococci.葡萄球菌群体中脱氧核糖核酸酶的产生
Zentralbl Bakteriol Orig. 1968 Feb;206(1):41-5.
引用本文的文献
1
Natural and artificial sources of genetic variation used in crop breeding: A baseline comparator for genome editing.作物育种中使用的遗传变异的自然和人工来源：基因组编辑的基线比较器。
Front Genome Ed. 2022 Aug 22;4:937853. doi: 10.3389/fgeed.2022.937853. eCollection 2022.
2
Water-Soluble Photoinitiators in Biomedical Applications.生物医学应用中的水溶性光引发剂
Polymers (Basel). 2020 May 7;12(5):1073. doi: 10.3390/polym12051073.
3
Evaluating ultraviolet sensitivity of adventitious agents in biopharmaceutical manufacturing.评估生物制药生产中偶发因子的紫外线敏感性。
J Ind Microbiol Biotechnol. 2017 Jun;44(6):893-909. doi: 10.1007/s10295-017-1917-0. Epub 2017 Mar 10.
4
Co-transduction of plasmids mediating resistance to tetracycline and chloramphenicol in Staphylococcus aureus.介导金黄色葡萄球菌对四环素和氯霉素耐药性的质粒共转导
J Bacteriol. 1974 Nov;120(2):934-4. doi: 10.1128/jb.120.2.934-944.1974.
5
Isolation of the rec mutants in Staphylococcus aureus.金黄色葡萄球菌中rec突变体的分离
J Bacteriol. 1972 Dec;112(3):1169-76. doi: 10.1128/jb.112.3.1169-1176.1972.
6
Role of beta-lactamases and outer membrane proteins in multiple beta-lactam resistance of Enterobacter cloacae.β-内酰胺酶和外膜蛋白在阴沟肠杆菌多重β-内酰胺耐药中的作用
Antimicrob Agents Chemother. 1985 Apr;27(4):455-9. doi: 10.1128/AAC.27.4.455.
7
Genetic analysis of Staphylococcus aureus with Tn4001.金黄色葡萄球菌Tn4001的基因分析
J Bacteriol. 1989 Jul;171(7):3968-72. doi: 10.1128/jb.171.7.3968-3972.1989.
8
Characterization and genetic mapping of a mutation affecting apurinic endonuclease activity in Staphylococcus aureus.金黄色葡萄球菌中影响脱嘌呤内切酶活性的突变的鉴定与基因定位
J Bacteriol. 1986 Nov;168(2):708-14. doi: 10.1128/jb.168.2.708-714.1986.
本文引用的文献
1
Transduction of resistance to chlortetracycline and novobiocin in Staphylococcus aureus.金黄色葡萄球菌对金霉素和新生霉素耐药性的转导
J Bacteriol. 1961 Dec;82(6):875-81. doi: 10.1128/jb.82.6.875-881.1961.
2
TRANSDUCTION ANALYSIS OF THE HISTIDINE REGION IN STAPHYLOCOCCUS AUREUS.金黄色葡萄球菌组氨酸区域的转导分析
J Gen Microbiol. 1965 May;39:195-207. doi: 10.1099/00221287-39-2-195.
3
Vulnerability of nucleic acids in mutant staphylococci with impaired respiration.呼吸受损的突变葡萄球菌中核酸的脆弱性。
J Gen Microbiol. 1962 Oct;29:317-23. doi: 10.1099/00221287-29-2-317.
4
Transduction of resistance to some macrolide antibiotics in Staphylococcus aureus.金黄色葡萄球菌对某些大环内酯类抗生素耐药性的转导
J Bacteriol. 1962 Nov;84(5):1049-55. doi: 10.1128/jb.84.5.1049-1055.1962.
5
Absence of repair of photodynamically induced damage in two mutants of Proteus mirabilis with increased sensitivity to monofunctional alkylating agents.
Mutat Res. 1968 Jul-Aug;6(1):166-8. doi: 10.1016/0027-5107(68)90112-7.
6
DNA repair mechanisms and their relation to mutation and recombination.DNA修复机制及其与突变和重组的关系。
Curr Top Microbiol Immunol. 1968;44:1-85.
7
Transduction studies on the role of a rec+ gene in the ultraviolet induction of prophage lambda.关于rec+基因在紫外线诱导噬菌体λ原噬菌体过程中作用的转导研究。
J Mol Biol. 1967 Jan 28;23(2):117-33. doi: 10.1016/s0022-2836(67)80021-4.
8
9
Repair of deoxyribonucleic acid in Haemophilus influenzae. I. X-ray sensitivity of ultraviolet-sensitive mutants and their behavior as hosts to ultraviolet-irradiated bacteriophage and transforming deoxyribonucleic acid.流感嗜血杆菌中脱氧核糖核酸的修复。I. 紫外线敏感突变体的X射线敏感性及其作为紫外线照射噬菌体和转化脱氧核糖核酸宿主的行为。
J Bacteriol. 1968 Feb;95(2):546-58. doi: 10.1128/jb.95.2.546-558.1968.
10
Ultraviolet-induced mutation and DNA repair.紫外线诱导的突变与DNA修复。
Annu Rev Microbiol. 1969;23:487-514. doi: 10.1146/annurev.mi.23.100169.002415.
Zotero 插件