Turner G A
Experientia. 1979 Dec 15;35(12):1657-8. doi: 10.1007/BF01953252.
The ability of collagenase to disaggregate a solid metastasizing lymphosarcoma has been shown to considerably increase with reducing environmental pH. It is suggested that this effect may be operating in vivo to release cells from a primary tumour.
胶原酶分解实体转移性淋巴肉瘤的能力已被证明会随着环境pH值的降低而显著增强。有人认为,这种效应可能在体内发挥作用,使细胞从原发性肿瘤中释放出来。