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未成熟和成熟家鸡肝脏中脂肪生成酶和糖酵解酶活性的研究

An investigation of lipogenic and glycolytic enzyme activity in the liver of sexually immature and mature domestic fowl.

作者信息

Pearce J

出版信息

Biochem J. 1971 Aug;123(5):717-9. doi: 10.1042/bj1230717.

DOI:10.1042/bj1230717
PMID:4256531
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1177072/
Abstract

In the non-laying pullet and the cockerel it was observed that there was no significant variation in the activities of ATP citrate lyase and ;malic' enzyme whereas in the laying hen there was a significantly greater activity of both these enzymes. Parallel increases in liver lipid content in the laying hen were also observed. Three glycolytic enzymes, phosphofructokinase, fructose diphosphate aldolase and pyruvate kinase, did not exhibit any significant variation in enzyme activity with the onset of egg laying. These results are discussed in relation to the hormonal status of the birds and also the demands of egg production for lipid.

摘要

在非产蛋小母鸡和小公鸡中,观察到ATP柠檬酸裂解酶和苹果酸酶的活性没有显著变化,而在产蛋母鸡中,这两种酶的活性显著更高。同时还观察到产蛋母鸡肝脏脂质含量也相应增加。三种糖酵解酶,即磷酸果糖激酶、果糖二磷酸醛缩酶和丙酮酸激酶,在开始产蛋时酶活性没有表现出任何显著变化。结合鸟类的激素状态以及产蛋对脂质的需求对这些结果进行了讨论。

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本文引用的文献

1
Changes in lipid synthesis in rat liver during development.大鼠肝脏发育过程中脂类合成的变化。
Biochem J. 1967 Mar;102(3):952-8. doi: 10.1042/bj1020952.
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Effect of functional hepatectomy upon estrogen-induced lipemia in the fowl.
Am J Physiol. 1951 Jun;165(3):600-3. doi: 10.1152/ajplegacy.1951.165.3.600.
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CITRATE AND THE CONVERSION OF CARBOHYDRATE INTO FAT. THE ACTIVITIES OF CITRATE-CLEAVAGE ENZYME AND ACETATE THIOKINASE IN LIVERS OF STARVED AND RE-FED RATS.柠檬酸盐与碳水化合物向脂肪的转化。饥饿和重新喂食大鼠肝脏中柠檬酸裂解酶和乙酸硫激酶的活性。
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SEX DIFFERENCES IN THE COMPOSITION AND ACETATE CORPORATION INTO LIVER LIPIDS OF THE ADULT FOWL.成年家禽肝脏脂质组成及乙酸掺入的性别差异
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PATTERNS OF DIETARY AND HORMONAL INDUCTION OF CERTAIN NADP-LINKED LIVER ENZYMES.某些与烟酰胺腺嘌呤二核苷酸磷酸(NADP)相关的肝脏酶的饮食和激素诱导模式。
Am J Physiol. 1964 Feb;206:357-61. doi: 10.1152/ajplegacy.1964.206.2.357.
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The synthesis of phosphoenolpyruvate in the gluconeogenesis. Enzyme levels of chick embryo livers.糖异生过程中磷酸烯醇式丙酮酸的合成。鸡胚肝脏的酶水平。
Eur J Biochem. 1967 Dec;3(1):19-24. doi: 10.1111/j.1432-1033.1967.tb19494.x.
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The citrate cleavage enzyme activity in chick embryo and chicken liver during development.发育过程中鸡胚和鸡肝脏中的柠檬酸裂解酶活性。
Experientia. 1967 Dec 15;23(12):1000-1. doi: 10.1007/BF02136408.
8
Lipid biosynthesis and transport in the domestic chick (Gallus domesticus).家鸡(原鸡)中的脂质生物合成与转运
Comp Biochem Physiol. 1969 Jul 1;30(1):149-59. doi: 10.1016/0010-406x(69)91309-7.
9
Adaptation of the laying hens (Gallus domesticus) to dietary fat with special reference to changes in liver and ovarian lipid content and liver enzyme activity.蛋鸡(家鸡)对日粮脂肪的适应性,特别提及肝脏和卵巢脂质含量以及肝脏酶活性的变化。
Comp Biochem Physiol. 1969 May;29(2):539-50. doi: 10.1016/0010-406x(69)91605-3.
10
The effect of starvation and starvation followed by feeding on enzyme activity and the metabolism of [U-14C]glucose in liver from growing chicks.饥饿以及饥饿后再喂食对生长中雏鸡肝脏中酶活性和[U-14C]葡萄糖代谢的影响。
Biochem J. 1968 Jul;108(4):667-73. doi: 10.1042/bj1080667.