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依赖脱氧核糖核酸的脱氧核糖核酸聚合酶与痘病毒的结合。

Binding of deoxyribonucleic acid-dependent deoxyribonucleic acid polymerase to poxvirus.

作者信息

Tan K B, McAuslan B R

出版信息

J Virol. 1972 Jan;9(1):70-4. doi: 10.1128/JVI.9.1.70-74.1972.

Abstract

Poxvirus has a deoxyribonucleic acid polymerase activity that remains associated with the virus despite repeated centrifugation through sucrose gradients. Highly purified poxvirus preparation can adsorb deoxyribonucleic acid polymerase from cytoplasmic extracts of cells containing such an activity. These results indicate that caution must be used in assuming that an enzyme associated with a purified virus is necessarily an integral part of the virion.

摘要

痘病毒具有一种脱氧核糖核酸聚合酶活性,即使通过蔗糖梯度反复离心,该活性仍与病毒相关联。高度纯化的痘病毒制剂能够从含有这种活性的细胞胞质提取物中吸附脱氧核糖核酸聚合酶。这些结果表明,在假定与纯化病毒相关联的一种酶必然是病毒粒子的一个组成部分时必须谨慎。

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本文引用的文献

1
2
DNA polymerase activity associated with purified Kilham rat virus.
Nat New Biol. 1971 Jun 9;231(23):174-6. doi: 10.1038/newbio231174a0.
4
Poxvirus DNA-dependent RNA polymerase.痘病毒DNA依赖性RNA聚合酶。
Proc Natl Acad Sci U S A. 1967 Jul;58(1):134-41. doi: 10.1073/pnas.58.1.134.

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