Roy R S
Can J Comp Med. 1972 Jan;36(1):1-8.
Strains of enterobacteria (nine and two ) isolated from primary or secondary infections in the dog, cat, pig, calf and kangaroo were studied for the presence of extrachromosomal drug resistance factors (R factors). Seven strains of and two strains of transferred resistance involving the following antibiotics: streptomycin, ampicillin, chloramphenicol, neomycin and tetracycline. All strains harboring R factors transferred streptomycin resistance and the identified resistance patterns were as follows: Sm Am, Sm Te, Sm Neo, Sm Am Te, Sm CI Neo and Sm Am CI Te. The levels of resistance observed were comparable for all donor strains and their converted recipients. Strains of harboring R factors were isolated from three dogs that had died of either otitis (followed by a generalized infection), enteritis or bronchopneumonia — secondary to distemper. The bacteria isolated from cats were recovered at the necropsy of animals that had died of purulent pleuresy and feline panleukopenia. The other strains (two and one were isolated from fatal enteric diseases in the pig, calf and kangaroo.
对从狗、猫、猪、小牛和袋鼠的原发性或继发性感染中分离出的肠杆菌菌株（9株和2株）进行了研究，以检测其是否存在染色体外耐药因子（R因子）。7株和2株转移了对以下抗生素的耐药性：链霉素、氨苄青霉素、氯霉素、新霉素和四环素。所有携带R因子的菌株都转移了链霉素耐药性，鉴定出的耐药模式如下：Sm Am、Sm Te、Sm Neo、Sm Am Te、Sm CI Neo和Sm Am CI Te。所有供体菌株及其转化受体观察到的耐药水平相当。携带R因子的菌株从三只死于中耳炎（继之以全身感染）、肠炎或支气管肺炎（继发于犬瘟热）的狗中分离得到。从猫身上分离出的细菌是在死于化脓性胸膜炎和猫泛白细胞减少症的动物尸检时获得的。其他菌株（2株和1株）从猪、小牛和袋鼠的致命肠道疾病中分离得到。
