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51-铬标记红细胞在小型猪体内的半衰期消失情况。

51-chromium labeled erythrocyte half-time disappearance from miniature swine.

作者信息

Mulder J B, Brown R V, Corwin L A

出版信息

Can J Comp Med. 1972 Apr;36(2):103-7.

PMID:4259922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1319627/
Abstract

Half-time disappearance of (51)Cr-laeled erythrocytes was studied in 39 Sinclair miniature swine at 20 to 46 days of age and again at 79 to 109 days of age. Mean erythrocyte half-time disappearance, disregarding age, was 21.29 (+/-0.77) days for males and 22.04 (+/-0.81) days for females. The half-time difference between males and females was not statistically significant (P<0.05). At 20 to 46 days of age the mean erythrocyte half-time disappearance was 19.56 (+/-1.41) days. The same pigs, tested at 79 to 109 days of age, had a mean erythrocyte half-time disappearance of 23.95 (+/-1.94) days. There was a significant difference (P<0.01) in erythrocyte half-time disappearance from miniature swine as the result of age and also for age within sex. The grand mean erythrocyte half-time disappearance, for all the miniature swine tested, was 21.67 (+/-0.54) days. The estimate of heritability was 0.61 for dam effect at 20 to 46 days of age and 0.06 at 79 to 109 days of age. Sire estimate of heritability was 0 at both age groups. It was concluded that the large heritability coefficient found only for dam component in young nursing pigs was the result of maternal environment rather than additive genetic variance.

摘要

对39头辛克莱小型猪在20至46日龄时以及再次在79至109日龄时进行了(51)铬标记红细胞半衰期消失情况的研究。不考虑年龄因素,雄性红细胞平均半衰期消失时间为21.29(±0.77)天,雌性为22.04(±0.81)天。雄性和雌性之间的半衰期差异无统计学意义(P<0.05)。在20至46日龄时,红细胞平均半衰期消失时间为19.56(±1.41)天。同一批猪在79至109日龄时进行测试,红细胞平均半衰期消失时间为23.95(±1.94)天。由于年龄以及性别内的年龄因素,小型猪红细胞半衰期消失情况存在显著差异(P<0.01)。所有测试的小型猪红细胞平均半衰期消失时间为21.67(±0.54)天。20至46日龄时母系效应的遗传力估计值为0.61,79至109日龄时为0.06。两个年龄组父系遗传力估计值均为0。得出的结论是,仅在幼龄哺乳仔猪母系成分中发现的高遗传力系数是母系环境而非加性遗传方差的结果。

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51-chromium labeled erythrocyte half-time disappearance from miniature swine.51-铬标记红细胞在小型猪体内的半衰期消失情况。
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本文引用的文献

1
Erythrocyte life span in growing swine as determined by glycine-2-C14.用甘氨酸-2-C14测定生长猪的红细胞寿命。
J Exp Med. 1955 May 1;101(5):451-9. doi: 10.1084/jem.101.5.451.
2
Red cell volume and red cell survival in normal aged people.正常老年人的红细胞体积与红细胞存活情况
J Clin Pathol. 1962 Jul;15(4):343-5. doi: 10.1136/jcp.15.4.343.
3
Survival of Cr-51 labeled erythrocytes in swine.铬-51标记的猪红细胞的存活情况
Proc Soc Exp Biol Med. 1963 Mar;112:573-6.
4
Life span of red blood cell.红细胞的寿命
Physiol Rev. 1959 Jul;39(3):577-616. doi: 10.1152/physrev.1959.39.3.577.
5
The ageing of red cells.红细胞的老化
J Physiol. 1958 Sep 23;143(2):325-31. doi: 10.1113/jphysiol.1958.sp006062.
6
The survival of Cr51-labeled autogenous erythrocytes in children.儿童体内铬51标记的自体红细胞的存活情况。
J Lab Clin Med. 1958 May;51(5):753-5.
7
The kinetics of iron metabolism in swine with various experimentally induced anemias.不同实验性诱导贫血猪的铁代谢动力学
J Exp Med. 1956 Jan 1;103(1):161-71. doi: 10.1084/jem.103.1.161.
8
The kinetics of iron metabolism in normal growing swine.正常生长猪铁代谢的动力学
J Exp Med. 1956 Jan 1;103(1):145-59. doi: 10.1084/jem.103.1.145.
9
51-chromium-labeled erythrocyte half-time in rhesus monkeys (Macaca mulatta).恒河猴(猕猴属)中51铬标记红细胞的半衰期
Lab Anim Sci. 1971 Dec;21(6):870-2.