Tuveson R W
J Bacteriol. 1972 Oct;112(1):632-4. doi: 10.1128/jb.112.1.632-634.1972.
Two independently segregating ultraviolet (UV) sensitivity genes in Neurospora crassa interact synergistically resulting in UV sensitivity approximately twice that expected based on an evaluation of the sensitivities of the individual mutants. The mutant genes singly and together reduce photoreactivation (PR) in vivo although a PR enzyme is produced which exhibits normal activity in vitro.
粗糙脉孢菌中两个独立分离的紫外线(UV)敏感性基因协同作用,导致紫外线敏感性约为根据对单个突变体敏感性评估所预期的两倍。尽管产生了一种在体外表现出正常活性的光复活(PR)酶,但这些突变基因单独或共同作用都会降低体内的光复活作用。