Chattopadhyay S K, Kohne D E, Dutta S K
Proc Natl Acad Sci U S A. 1972 Nov;69(11):3256-9. doi: 10.1073/pnas.69.11.3256.
DNA sequences in Neurospora crassa that code for ribosomal RNA have been isolated in a highly purified state by DNA-RNA hybridization. About 100 separate ribosomal RNA genes exist in each nucleus. These genes are composed of repeated sequences that are present about 100 times per nucleus. The individual members of this group of DNA sequences are essentially identical.
通过DNA-RNA杂交技术,已经以高度纯化的状态分离出了粗糙脉孢菌中编码核糖体RNA的DNA序列。每个细胞核中大约存在100个独立的核糖体RNA基因。这些基因由重复序列组成,每个细胞核中大约存在100次。这组DNA序列的各个成员基本相同。