Campisi D, Whitcomb C
Arch Intern Med. 1979 Mar;139(3):365-6.
Atypical manifestations of early syphilis, although uncommon, may represent diagnostic difficulties and delay therapy. We describe two cases of hepatitis complicating early syphilis. Clues to the diagnosis of early syphilitic hepatitis include the presence of perianal lesions and disproportionate increases in the serum alkaline phosphatase level. Biopsy results were nonspecific. The major differential diagnostic consideration is hepatitis B with false-positive serologic findings. The abnormalities of liver function respond to standard therapy for secondary syphilis. Follow-up of patients and their contacts is essential.
早期梅毒的非典型表现虽不常见，但可能造成诊断困难并延误治疗。我们描述了两例并发早期梅毒的肝炎病例。早期梅毒肝炎的诊断线索包括存在肛周病变以及血清碱性磷酸酶水平不成比例升高。活检结果不具有特异性。主要的鉴别诊断考虑是伴有血清学假阳性结果的乙型肝炎。肝功能异常对二期梅毒的标准治疗有反应。对患者及其接触者进行随访至关重要。
