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夏威夷不同种族系统性红斑狼疮的发病率

Frequency of systemic lupus erythematosus in different ethnic groups in Hawaii.

作者信息

Serdula M K, Rhoads G G

出版信息

Arthritis Rheum. 1979 Apr;22(4):328-33. doi: 10.1002/art.1780220403.

DOI:10.1002/art.1780220403
PMID:426879
Abstract

A survey of systemic lupus erythematosus (SLE) patients was conducted in civilian general hospitals on Oahu, Hawaii for the years 1970-75. One hundred sixty-eight cases were ascertained, of which 107 were considered "definite." Age-adjusted prevalence rates per 100,000 were estimated for definite cases at the end of 1975 as follows: white 5.8, Chinese 24.1, Filipino 19.9, part-Hawaiian 20.4, and Japanese 18.2. There was a heavy preponderance of females in each ethnic group, averaging 90% of the definite cases overall. Review of vital statistics for the United States and Hawaii during this period showed age-adjusted SLE mortality rates per million as follows: U.S. white 3.04, U.S. non-white 8.82, Hawaii white 1.89, Hawaii non-white 14.46. The cause of the very high SLE prevalence and mortality in the Oriental and Polynesian people of Hawaii is not clear.

摘要

1970年至1975年期间,在夏威夷瓦胡岛的民用综合医院对系统性红斑狼疮(SLE)患者进行了一项调查。共确诊168例病例,其中107例被视为“确诊”。1975年底,对确诊病例每10万人的年龄调整患病率进行了如下估计:白人5.8,华人24.1,菲律宾人19.9,部分夏威夷人20.4,日本人18.2。每个种族群体中女性占绝大多数,总体上确诊病例平均占90%。对这一时期美国和夏威夷的生命统计数据进行回顾后发现,每百万人口的年龄调整SLE死亡率如下:美国白人3.04,美国非白人8.82,夏威夷白人1.89,夏威夷非白人14.46。夏威夷的东方人和波利尼西亚人SLE患病率和死亡率极高的原因尚不清楚。

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