Smith H R, Grindley N D, Humphreys G O, Anderson E S
J Bacteriol. 1973 Aug;115(2):623-8. doi: 10.1128/jb.115.2.623-628.1973.
The four R factors described in this paper form a single compatibility group which has been previously designated group H. Recombination was demonstrated between any pair of the plasmids TP117, 123, and 124. In contrast, TP116 did not appear to recombine with any other members of the group. TP117, 123, and 124 usually displaced the F factor from Escherichia coli K-12F(+), while TP116 and F coexisted stably in that strain. Deoxyribonucleic acid reassociation experiments showed minimal homology between F and the four group H plasmids. The results indicate that there are limitations to using incompatibility alone for classification of bacterial plasmids.
本文所述的四个R因子形成了一个单一的相容性群，该群先前被指定为H群。已证明质粒TP117、123和124中的任意两个之间会发生重组。相比之下，TP116似乎不会与该群的任何其他成员发生重组。TP117、123和124通常会从大肠杆菌K-12F(+)中取代F因子，而TP116和F在该菌株中稳定共存。脱氧核糖核酸重结合实验表明F与四个H群质粒之间的同源性极小。结果表明，仅使用不相容性对细菌质粒进行分类存在局限性。
