• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人心肌中儿茶酚胺的浓度。

Concentration of catecholamines in human cardiac muscle.

作者信息

Petch M C, Nayler W G

出版信息

Br Heart J. 1979 Mar;41(3):340-4. doi: 10.1136/hrt.41.3.340.

DOI:10.1136/hrt.41.3.340
PMID:426982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC482037/
Abstract

A trihydroxyindole fluorescent technique was used to measure the concentration of catecholamines in heart muscle taken from 42 patients undergoing open heart surgery. Noradrenaline was the dominant catecholamine and its depletion in the failing heart was confirmed. The distribution of catecholamines within the heart was such that the highest value, 2.64 +/- 0.68 microgram/g, was found in the nonfailing right atrium and the lowest, 0.53 +/- 0.40 microgram/g, in the failing left ventricle.

摘要

采用三羟基吲哚荧光技术测定了42例接受心脏直视手术患者心肌中儿茶酚胺的浓度。去甲肾上腺素是主要的儿茶酚胺,且证实其在衰竭心脏中减少。心脏内儿茶酚胺的分布情况为:在无衰竭的右心房中最高,为2.64±0.68微克/克;在衰竭的左心室中最低,为0.53±0.40微克/克。

相似文献

1
Concentration of catecholamines in human cardiac muscle.人心肌中儿茶酚胺的浓度。
Br Heart J. 1979 Mar;41(3):340-4. doi: 10.1136/hrt.41.3.340.
2
Uptake of catecholamines by human cardiac muscle in vitro.体外培养的人心脏肌肉对儿茶酚胺的摄取。
Br Heart J. 1979 Mar;41(3):336-9. doi: 10.1136/hrt.41.3.336.
3
[Noradrenaline and adrenaline content in the myocardium and heart conduction system in humans and animals after trauma].
Kardiologiia. 1981 Oct;21(10):110-2.
4
(-)-Adrenaline elicits positive inotropic, lusitropic, and biochemical effects through beta2 -adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consistent with Gs coupling but not with Gi coupling.(-)-肾上腺素通过非衰竭和衰竭心脏的人心房心肌中的β2-肾上腺素能受体引发正性肌力、变时性和生化效应,这与Gs偶联一致,但与Gi偶联不一致。
Naunyn Schmiedebergs Arch Pharmacol. 2007 Mar;375(1):11-28. doi: 10.1007/s00210-007-0138-x. Epub 2007 Feb 13.
5
Studies on the relationship between the catecholamine distribution in the atrium and the specific granules present in atrial muscle cells. 2. Studies on the sedimentation pattern of atrial noradrenaline and adrenaline.1. 心房中儿茶酚胺分布与心房肌细胞中特定颗粒之间关系的研究。2. 心房去甲肾上腺素和肾上腺素沉降模式的研究。
Cardiovasc Res. 1973 May;7(3):364-9. doi: 10.1093/cvr/7.3.364.
6
[Changes of catecholamine content in the myocardium in thyrotoxicosis].[甲状腺毒症时心肌中儿茶酚胺含量的变化]
Kardiologiia. 1976 May;16(5):99-102.
7
[Noradrenaline and adrenaline content in different areas of the heart in patients dying of myocardial infarct].
Kardiologiia. 1975 Oct;15(10):102-7.
8
An improved method for the fluorometric determination of tissue catecholamines.一种改进的荧光法测定组织儿茶酚胺的方法。
Neurochem Res. 1986 May;11(5):753-8. doi: 10.1007/BF00965343.
9
The effect of experimental heart insufficiency on the content of catecholamines in the heart, spleen and kidneys and on the fluorescence reaction of the adrenergic nerve fibres in rats.
Acta Pharmacol Toxicol (Copenh). 1967;25:Suppl 4:14-5. doi: 10.1111/j.1600-0773.1967.tb03009.x.
10
Effects of transient occlusion of coronary circulation on catecholamine and electrolyte gradients in human atrium.冠状动脉循环短暂闭塞对人心房儿茶酚胺和电解质梯度的影响。
Br Heart J. 1971 Jul;33(4):609.

引用本文的文献

1
Histamine can be Formed and Degraded in the Human and Mouse Heart.组胺可在人和小鼠心脏中生成与降解。
Front Pharmacol. 2021 May 11;12:582916. doi: 10.3389/fphar.2021.582916. eCollection 2021.
2
Functional differences between junctional and extrajunctional adrenergic receptor activation in mammalian ventricle.哺乳动物心室中连接和非连接肾上腺素能受体激活的功能差异。
Am J Physiol Heart Circ Physiol. 2013 Feb 15;304(4):H579-88. doi: 10.1152/ajpheart.00754.2012. Epub 2012 Dec 15.
3
Determination of endogenous norepinephrine levels in different chambers of the rat heart by capillary electrophoresis coupled with amperometric detection.采用毛细管电泳-安培检测法测定大鼠心脏不同腔室内内源性去甲肾上腺素水平。
J Neurosci Methods. 2007 Jun 15;163(1):52-9. doi: 10.1016/j.jneumeth.2007.02.008. Epub 2007 Feb 16.
4
Profound cardiac sympathetic denervation occurs in Parkinson disease.帕金森病会出现严重的心脏交感神经去神经支配。
Brain Pathol. 2005 Jan;15(1):29-34. doi: 10.1111/j.1750-3639.2005.tb00097.x.
5
Cardiac death prediction and impaired cardiac sympathetic innervation assessed by MIBG in patients with failing and nonfailing hearts.通过间碘苄胍(MIBG)评估心脏功能衰竭和未衰竭患者的心脏死亡预测及心脏交感神经支配受损情况。
J Nucl Cardiol. 1998 Nov-Dec;5(6):579-90. doi: 10.1016/s1071-3581(98)90112-x.
6
Histamine release from human right atrium.组胺从人右心房释放。
Br J Pharmacol. 1981 Sep;74(1):7-9. doi: 10.1111/j.1476-5381.1981.tb09947.x.
7
The inotropic effects of dopamine and its precursor levodopa on isolated human ventricular myocardium.多巴胺及其前体左旋多巴对离体人心室肌的变力作用。
Klin Wochenschr. 1985 Nov 4;63(21):1117-23. doi: 10.1007/BF02291093.
8
Uptake of catecholamines by human cardiac muscle in vitro.体外培养的人心脏肌肉对儿茶酚胺的摄取。
Br Heart J. 1979 Mar;41(3):336-9. doi: 10.1136/hrt.41.3.336.

本文引用的文献

1
REGIONAL DISTRIBUTION OF CATECHOLAMINES IN THE DOG HEART.狗心脏中儿茶酚胺的区域分布
Circ Res. 1965 Jan;16:39-44. doi: 10.1161/01.res.16.1.39.
2
CHEMICAL AND HISTOCHEMICAL EVALUATION OF THE DISTRIBUTION OF CATECHOLAMINES IN THE RABBIT AND GUINEA PIG HEARTS.兔和豚鼠心脏中儿茶酚胺分布的化学及组织化学评估
Acta Physiol Scand. 1963 Sep-Oct;59:184-92. doi: 10.1111/j.1748-1716.1963.tb02734.x.
3
MYOCARDIAL NOREPINEPHRINE CONCENTRATION IN MAN. EFFECTS OF RESERPINE AND OF CONGESTIVE HEART FAILURE.人体心肌去甲肾上腺素浓度。利血平和充血性心力衰竭的影响。
N Engl J Med. 1963 Sep 26;269:653-8. doi: 10.1056/NEJM196309262691302.
4
A study of the factors affecting the aluminum oxide-trihydroxyindole procedure for the analysis of catecholamines.一项关于影响用于儿茶酚胺分析的氧化铝 - 三羟基吲哚法的因素的研究。
J Pharmacol Exp Ther. 1962 Dec;138:360-75.
5
Distribution of norepinephrine in the heart.去甲肾上腺素在心脏中的分布。
Nature. 1958 Mar 22;181(4612):848-9. doi: 10.1038/181848a0.
6
Mechanism of norepinephrine depletion in experimental heart failure produced by aortic constriction in the guinea pig.豚鼠主动脉缩窄所致实验性心力衰竭中去甲肾上腺素耗竭的机制
Circ Res. 1965 Oct;17(4):312-21. doi: 10.1161/01.res.17.4.312.
7
Catecholamine uptake processes.儿茶酚胺摄取过程
Br Med Bull. 1973 May;29(2):130-5. doi: 10.1093/oxfordjournals.bmb.a070982.
8
Biochemical analyses of human papillary muscles and guinea pig ventricles in failure.衰竭状态下人类乳头肌和豚鼠心室的生化分析。
Proc Soc Exp Biol Med. 1970 Dec;135(3):817-24. doi: 10.3181/00379727-135-35151.
9
The effects of acute administration of propranolol and practolol on the uptake, content, release, and turnover of noradrenaline in the rat heart in vivo.
Naunyn Schmiedebergs Arch Pharmacol. 1974;282(1):85-96. doi: 10.1007/BF00647405.
10
Norepinephrine metabolism in hypertrophied rat hearts.肥厚型大鼠心脏中的去甲肾上腺素代谢
Nature. 1965 Aug 28;207(5000):951-3. doi: 10.1038/207951a0.