Petch M C, Nayler W G
Br Heart J. 1979 Mar;41(3):336-9. doi: 10.1136/hrt.41.3.336.
Noradrenaline uptake was studied using heart muscle from 102 patients undergoing cardiac surgery. Slices of right atrium were incubated in Krebs-Henseleit solution containing 1.3 x 10(-7) M 3H-noradrenaline. Uptake was lower in failing heart muscle and was inhibited not only by increasing the noradrenaline concentration in the incubating medium but also by adding the drugs desmethylimipramine, amitryptyline, and ouabain.
使用102例接受心脏手术患者的心肌研究去甲肾上腺素摄取。将右心房切片置于含有1.3×10⁻⁷M³H - 去甲肾上腺素的克雷布斯 - 亨塞尔特溶液中孵育。衰竭心肌中的摄取较低，不仅通过增加孵育培养基中去甲肾上腺素的浓度，而且通过添加药物去甲丙咪嗪、阿米替林和哇巴因来抑制摄取。
