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老年性盘状黄斑变性:提示适合光凝治疗的特征

Senile disciform macular degeneration: features indicating suitability for photocoagulation.

作者信息

Grey R H, Bird A C, Chisholm I H

出版信息

Br J Ophthalmol. 1979 Feb;63(2):85-9. doi: 10.1136/bjo.63.2.85.

Abstract

During a 1-year period 398 new patients were seen with disciform macular degeneration (530 eyes). The lesions were studied retrospectively, and those in which the neovascular tissue did not underlie the fovea, and therefore were treatable, were identified. The following conclusions were drawn: (1) Treatment is possible in most patients with good acuity and few with poor acuity. (2) Treatment is possible in a large proportion of patients with a short history and few with a long history of visual loss. (3) As many as 50% of all patients with senile disciform macular degeneration may be amenable to treatment if seen early enough in the course of their disease. (4) Over one-third of eyes with lesions that are untreated have a visual acuity of 6/60 or better 3 years after the onset of symptoms. (5) If a controlled trial proves that treatment is beneficial, these results emphasise the need for rapid referral and show that these patients will generate a large additional clinical load.

摘要

在1年期间,共诊治了398例盘状黄斑变性新患者(530只眼)。对这些病变进行了回顾性研究,确定了那些新生血管组织不在黄斑中心凹下方、因而可以治疗的病变。得出了以下结论:(1)大多数视力良好的患者可以接受治疗,而视力差的患者中少数也可以治疗。(2)在病程短的患者中,很大一部分可以接受治疗,而病程长的视力丧失患者中少数可以治疗。(3)如果在老年性盘状黄斑变性病程足够早期就进行诊治,所有患者中多达50%可能适合治疗。(4)三分之一以上未经治疗的病变眼在症状出现3年后视力为6/60或更好。(5)如果一项对照试验证明治疗有益,这些结果强调了快速转诊的必要性,并表明这些患者将带来大量额外的临床负担。

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本文引用的文献

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Laser photocoagulation of macular lesions.黄斑病变的激光光凝术。
Trans Am Acad Ophthalmol Otolaryngol. 1968 May-Jun;72(3):377-88.
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Can J Ophthalmol. 1970 Apr;5(2):117-26.
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Argon laser slit-lamp retinal photocoagulation.氩激光裂隙灯视网膜光凝术。
Trans Am Acad Ophthalmol Otolaryngol. 1970 Jan-Feb;74(1):85-97.
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Drusen and disciform macular detachment and degeneration.玻璃膜疣与盘状黄斑脱离及变性。
Arch Ophthalmol. 1973 Sep;90(3):206-17. doi: 10.1001/archopht.1973.01000050208006.
7
Exudative senile maculopathy. I. Results of argon laser treatment.渗出性老年黄斑病变。I. 氩激光治疗结果。
Arch Ophthalmol. 1973 Sep;90(3):183-96. doi: 10.1001/archopht.1973.01000050185003.

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