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母鼠和胎鼠肝脏中的超氧化物歧化酶(EC 1.15.1.1)、锌状态与乙醇消耗

Superoxide dismutase (EC 1.15.1.1), zinc status and ethanol consumption in maternal and foetal rat livers.

作者信息

Dreosti I E, Record I R

出版信息

Br J Nutr. 1979 Mar;41(2):399-402. doi: 10.1079/bjn19790049.

DOI:10.1079/bjn19790049
PMID:427092
Abstract
  1. The activity of superoxide dismutase (EC 1.15.1.1) was not greatly affected by zinc deficiency in maternal or foetal (20 d) rat livers, although in the latter tissue it did appear to be slightly raised by Zn depletion when compared with pair-fed control animals. 2. Enzyme activity was significantly higher in livers from all foetuses after administration of aqueous ethanol at 100 or 200 ml/l to the dams during pregnancy. 3. Plasma Zn levels were significantly increased in Zn-deficient dams after ingestion of alcohol during pregnancy.
摘要
  1. 超氧化物歧化酶(EC 1.15.1.1)的活性在母体或胎儿(20日龄)大鼠肝脏中受锌缺乏的影响不大,尽管与配对喂养的对照动物相比,在胎儿组织中,锌缺乏确实似乎会使其活性略有升高。2. 在孕期向母鼠给予浓度为100或200毫升/升的水性乙醇后,所有胎儿肝脏中的酶活性均显著升高。3. 孕期摄入酒精后,缺锌母鼠的血浆锌水平显著升高。

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引用本文的文献

1
Zinc deficiency and the developing embryo.锌缺乏与胚胎发育。
Biol Trace Elem Res. 1985 Mar;7(2):103-22. doi: 10.1007/BF02916569.
2
Zinc, ethanol, and lipid peroxidation in adult and fetal rats.锌、乙醇与成年和胎儿大鼠的脂质过氧化作用。
Biol Trace Elem Res. 1987 Dec;14(3):179-91. doi: 10.1007/BF02795685.