Noble P B, Boyarsky A, Bentley K C
Can J Physiol Pharmacol. 1979 Jan;57(1):108-12. doi: 10.1139/y79-016.
Using a time-lapse cinephotomicrographic technique, the locomotory paths taken by lymphocytes have been shown to satisfy the requirements for a continuous-time Markov chain analysis consisting of four directional states defined by the four quadrants of a Cartesian plane and state 0 in which the cells are stationary. The important parameters characterizing this path motion are the average time (waiting time) that a cell spends in each state and the state transition probabilites which, using the Markov model, allow the computation of the probability of the cells moving in a given direction. Our results show that lymphocytes moving alone on glass exhibit a random migration pattern.
通过延时电影显微摄影技术，已表明淋巴细胞所采取的运动路径满足连续时间马尔可夫链分析的要求，该分析由笛卡尔平面的四个象限定义的四个方向状态以及细胞静止的状态0组成。表征这种路径运动的重要参数是细胞在每个状态下花费的平均时间（等待时间）和状态转移概率，使用马尔可夫模型可以计算细胞在给定方向上移动的概率。我们的结果表明，在玻璃上单独移动的淋巴细胞呈现出随机迁移模式。
