Gastritic glandularis et cystica profunda: a report of three cases with discussion of etiology and pathogenesis.

Three cases of gastritis glandularis et cystica profunda are presented, two associated with severe chronic gastritis and the other with invasive gastric carcinoma and chronic gastritis. This poorly known entity consists of benign downgrowths of deep gastric glands through the muscularis mucosae into the submucosa. The pattern is primarily adenomatous with secondary cyst formation, which varies in extent and severity. The lesion is related to the chronic gastritis but why it should occur so rarely in such a common condition as chronic gastritis remains obscure. More documented cases are needed before a meaningful analysis can be attempted.