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人类混合淋巴细胞反应中的B淋巴母细胞。

B lymphoblasts in the human mixed lymphocyte reaction.

作者信息

Phillips B, Weisrose E

出版信息

Clin Exp Immunol. 1974 Sep;18(1):49-54.

Abstract

A proportion of the lymphoblasts in human mixed lymphocyte cultures (MLC) were shown by immunofluorescent staining to express surface immunoglobulin. Evidence was obtained to show that B lymphocytes may act as responders and stimulators: when enriched populations of B and T lymphocytes were prepared by means of immunoadsorbent columns, a mitogenic response was observed between T lymphocytes, B lymphocytes, and B and T lymphocytes established as MLC.

摘要

通过免疫荧光染色显示,人类混合淋巴细胞培养物(MLC)中的一部分淋巴母细胞表达表面免疫球蛋白。有证据表明B淋巴细胞可能作为反应细胞和刺激细胞:当通过免疫吸附柱制备B淋巴细胞和T淋巴细胞的富集群体时,在T淋巴细胞、B淋巴细胞以及作为MLC建立的B淋巴细胞和T淋巴细胞之间观察到有丝分裂反应。

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