处于分裂期的人淋巴细胞特异性膜抗原。
Membrane antigens specific for human lymphoid cells in the dividing phase.
作者信息
Thomas D B, Phillips B
出版信息
J Exp Med. 1973 Jul 1;138(1):64-70. doi: 10.1084/jem.138.1.64.
Abstract
Heteroantisera were raised in rabbits against human thymocytes or Burkitt's lymphoma EBI cells. After suitable absorption, the sera were specific for thymocytes and T lymphoblasts, or B lymphoblasts and several lymphoblastoid cell lines. The specificity of the antisera was confirmed by preparing purified populations of T or B lymphocytes on immunoabsorbent columns, followed by mitogenic stimulation with phytohemagglutinin. The antisera did not react with normal resting lymphocytes.
摘要
用兔制备了针对人胸腺细胞或伯基特淋巴瘤EBI细胞的异种抗血清。经过适当吸收后，这些血清对胸腺细胞和T淋巴母细胞，或B淋巴母细胞和几种淋巴母细胞样细胞系具有特异性。通过在免疫吸附柱上制备纯化的T或B淋巴细胞群体，然后用植物血凝素进行促有丝分裂刺激，证实了抗血清的特异性。这些抗血清与正常静止淋巴细胞无反应。
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