炎症性肠病中的直肠免疫球蛋白E细胞
Rectal IgE cells in inflammatory bowel disease.
作者信息
O'Donoghue D P, Kumar P
出版信息
Gut. 1979 Feb;20(2):149-53. doi: 10.1136/gut.20.2.149.
Abstract
Immunoglobulin-contained cells in the rectal mucosa of patients suffering from non-specific inflammatory bowel disease (IBD) were counted and compared with those in a control population. While the numbers of IgA, IgM, and IgG-containing cells in both ulcerative colitis and Crohn's disease did not differ from normal, both disease groups exhibited a marked increase in IgE-staining cells. This increase in IgE-cells did not correlate with severity, duration, or treatment of disease and it did not prove possible, using these immunological studies, to differentiate between Crohn's disease and ulcerative colitis.
摘要
对患有非特异性炎症性肠病（IBD）患者的直肠黏膜中含免疫球蛋白的细胞进行计数，并与对照组人群的细胞进行比较。虽然溃疡性结肠炎和克罗恩病中含IgA、IgM和IgG的细胞数量与正常情况并无差异，但两个疾病组中IgE染色细胞均显著增加。IgE细胞的这种增加与疾病的严重程度、病程或治疗无关，并且通过这些免疫学研究无法区分克罗恩病和溃疡性结肠炎。
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本文引用的文献
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