Skinner J M, Whitehead R
J Clin Pathol. 1974 Aug;27(8):643-6. doi: 10.1136/jcp.27.8.643.
Immunoglobulin-containing cells have been counted in the mucosa of colectomy specimens from patients with ulcerative colitis and Crohn's disease. An increase in IgA cells occurs in both when compared with normal. In Crohn's colitis the increase is significantly higher than in ulcerative colitis. The importance of these findings in relation to pathogenesis is discussed.
对溃疡性结肠炎和克罗恩病患者结肠切除标本的黏膜中含免疫球蛋白的细胞进行了计数。与正常情况相比,两者的IgA细胞均有所增加。在克罗恩结肠炎中,这种增加显著高于溃疡性结肠炎。讨论了这些发现与发病机制相关的重要性。