Nash C L, Gregg E C, Brown R H, Pillai K
J Bone Joint Surg Am. 1979 Apr;61(3):371-4.
Thirteen healthy teenage girls with idiopathic adolescent scoliosis were studied using multiple thermoluminescent dosimeters while undergoing standard diagnostic roentgenograms. Average organ doses for each anteroposterior and lateral examination were calculated for bone marrow, gastrointestinal tract, lungs, breast tissue, and gonads. Given an average of twenty-two roentgenograms over a three-year Milwaukee brace-treatment program, the increase in organ carcinogenic risk due to x-ray radiation ranged from 3.4 to fifteen per million (1.3 per cent to 7.5 per cent), except for breast tissue which increased from 140 to 290 per million (110 per cent). Using posteroanterior rather than anteroposterior exposures reduced the increased risk to 5.3 per million (3.8 per cent). The genetic risks of scoliosis roentgenographic studies were considered to be negligible, especially with gonadal shielding and infrequent roentgenograms made every three to four months. Good technique and judicious ordering of roentgenograms added significantly to the safety of the patient.
对13名患有特发性青少年脊柱侧凸的健康少女在进行标准诊断性X线检查时使用多个热释光剂量计进行了研究。计算了每次前后位和侧位检查时骨髓、胃肠道、肺、乳腺组织和性腺的平均器官剂量。在为期三年的密尔沃基支具治疗方案中，平均进行了22次X线检查，除乳腺组织的致癌风险从百万分之140增加到百万分之290（增加了110%）外，因X线辐射导致的器官致癌风险增加范围为百万分之3.4至15（0.13%至0.75%）。使用后前位而非前后位曝光可将增加的风险降低至百万分之5.3（0.38%）。脊柱侧凸X线检查的遗传风险被认为可以忽略不计，尤其是在采用性腺屏蔽且每三到四个月进行一次不频繁的X线检查时。良好的技术和审慎安排X线检查显著提高了患者的安全性。
