Remington J S, Merigan T C
Science. 1968 Aug 23;161(3843):804-6. doi: 10.1126/science.161.3843.804.
Chick and mouse cell monolayers treated with interferon were significantly protected from destruction by toxoplasma. The results suggest that fewer numbers of organisms were released from interferon-treated cells. Interferons were uniformly more active in a viral assay than in a toxoplasma assay, and they had the same properties in both assays. The data suggest that interferon activity may be directed against organisms phylogenetically higher than viruses.
用干扰素处理的鸡和小鼠细胞单层受到显著保护，免受弓形虫的破坏。结果表明，从经干扰素处理的细胞中释放出的生物体数量较少。干扰素在病毒检测中始终比在弓形虫检测中更具活性，并且它们在两种检测中具有相同的特性。数据表明，干扰素活性可能针对系统发育上高于病毒的生物体。
