Bulens C, De Vries W A, Van Crevel H
J Neurol Sci. 1979 Feb;40(2-3):147-57. doi: 10.1016/0022-510x(79)90200-4.
Thirty-six patients with benign intracranial hypertension (BIH) were reviewed. Follow-up was obtained on 33 patients (91%) after a mean period of 7 1/2 years. Precipitating factors were found in 27 patients (75%). On admission, 5 patients had retro-ocular pain, especially on eye movements, a complaint not yet described in BIH. Seven patients had nystagmus, two of them horizontal positional nystagmus. It is questionable whether all signs in BIH are caused by the raised CSF pressure. The general outcome was good. Only two patients sustained severe ultimate visual impairment. Both presented with retro-ocular pain and sudden loss of vision on admission. Papilloedema can persist for years in BIH without serious visual impairment. Sometimes "causal" treatment is possible. No symptomatic treatment which is free from complications has been proved to prevent visual failure.
对36例良性颅内高压(BIH)患者进行了回顾性研究。平均7.5年后,对33例患者(91%)进行了随访。在27例患者(75%)中发现了诱发因素。入院时,5例患者有眼球后疼痛,尤其是眼球运动时疼痛,这一症状在良性颅内高压中尚未见报道。7例患者有眼球震颤,其中2例为水平性位置性眼球震颤。良性颅内高压的所有体征是否均由脑脊液压力升高引起尚存在疑问。总体预后良好。只有2例患者最终出现严重视力损害。这2例患者入院时均有眼球后疼痛和视力突然丧失。视乳头水肿在良性颅内高压中可持续数年而无严重视力损害。有时可以进行“病因”治疗。尚未证明任何无并发症的对症治疗可预防视力丧失。