肝实质细胞膜中对胰高血糖素敏感的腺苷酸环化酶。
Glucagon-sensitive adenyl cylase in plasma membrane of hepatic parenchymal cells.
作者信息
Pohl S L, Birnbaumer L, Rodbell M
出版信息
Science. 1969 May 2;164(3879):566-7. doi: 10.1126/science.164.3879.566.
PMID:4305077
Abstract
The plasma membrane of hepatic parenchymal cells contains an adenyl cyclase system that is stimulated by glucagon. Adrenocorticotropin and epinephrine do not stimulate this adenyl cyclase, and very little cyclic phospho-diesterase activity is present in the membrane. These findings support the concept that glucagon exerts its regulatory action in the liver by stimulating adenyl cyclase activity in the plasma membrane.
摘要
肝实质细胞的质膜含有一种受胰高血糖素刺激的腺苷酸环化酶系统。促肾上腺皮质激素和肾上腺素不会刺激这种腺苷酸环化酶，并且质膜中存在的环磷酸二酯酶活性非常低。这些发现支持了这样一种概念，即胰高血糖素通过刺激质膜中的腺苷酸环化酶活性在肝脏中发挥其调节作用。
Zotero 插件