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17β-雌二醇对风疹病毒在雌激素反应性连续细胞系中复制的影响。

Effects of 17beta-estradiol on the replication of rubella virus in an estrogen-responsive, continuous cell line.

作者信息

Roehrig J T, Brawner T A, Riggs H G

出版信息

J Virol. 1979 Jan;29(1):417-20. doi: 10.1128/JVI.29.1.417-420.1979.

Abstract

A 70% reduction in the number of infectious rubella virions normally produced in MCF-7 cells occurred when the cells were stimulated with 17beta-estradiol. Analysis of virus-induced RNA indicated a delay in the conversion of replicative intermediate to virion RNA.

摘要

当用17β-雌二醇刺激MCF-7细胞时,正常情况下在这些细胞中产生的传染性风疹病毒粒子数量减少了70%。对病毒诱导的RNA的分析表明,复制中间体向病毒粒子RNA的转化出现延迟。

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