Konijn T M, van de Meene J G, Chang Y Y, Barkley D S, Bonner J T
J Bacteriol. 1969 Aug;99(2):510-2. doi: 10.1128/jb.99.2.510-512.1969.
Adenosine-3',5'-cyclic monophosphate was shown to be the compound found in Escherichia coli responsible for the attraction of the amoebae of the cellular slime mold Dictyostelium discoideum. A number of other nucleotides were tested and the following were active: tubercidin-3',5'-cyclic monophosphate, N(6)-2'-O-dibutyryl-adenosine-3',5'-cyclic monophosphate, 5'-methylene adenosine-3',5'-cyclic monophosphonate, guanosine-3',5'-cyclic monophosphate, uridine-3',5'-cyclic monophosphate, cytidine-3',5'-cyclic monophosphate, inosine-3',5'-cyclic monophosphate, and thymidine-3',5'-cyclic monophosphate. They were less active than adenosine-3',5'-cyclic monophosphate. It is suggested that cyclic adenosine monophosphate secreted by the bacteria is used by the amoebae as a means of sensing and orienting towards food.
已证明3',5'-环磷酸腺苷是大肠杆菌中发现的一种化合物，它可吸引细胞黏菌盘基网柄菌的变形虫。对其他多种核苷酸进行了测试，以下几种具有活性：结核菌素-3',5'-环磷酸、N(6)-2'-O-二丁酰-3',5'-环磷酸腺苷、5'-亚甲基腺苷-3',5'-环磷酸酯、3',5'-环磷酸鸟苷、3',5'-环磷酸尿苷、3',5'-环磷酸胞苷、3',5'-环磷酸肌苷和3',5'-环磷酸胸苷。它们的活性低于3',5'-环磷酸腺苷。有人提出，细菌分泌的环磷酸腺苷被变形虫用作感知食物并向食物定向的一种方式。
