Bonner J T, Hall E M, Sachsenmaier W, Walker B K
J Bacteriol. 1970 Jun;102(3):682-7. doi: 10.1128/jb.102.3.682-687.1970.
An unknown substance found in bacteria (Escherichia coli) is especially effective in attracting the vegetative amoebae of the cellular slime mold, Dictyostelium discoideum. However, the aggregating amoebae are not attracted to it at all. On the other hand, the vegetative amoebae show very little chemotactic response to cyclic adenosine monophosphate (cyclic AMP), whereas the aggregating amoebae are exceptionally responsive to it. It is suggested that the new factor may be used in food seeking, whereas cyclic AMP, the chemotactic substance responsible for aggregation, is the acrasin of this species. The important point is that the amoebae are differentially stage-specific in their responses to these two chemotactic agents.
在细菌（大肠杆菌）中发现的一种未知物质，对细胞黏菌盘基网柄菌的营养性变形虫具有特别强的吸引力。然而，聚集的变形虫对其完全没有反应。另一方面，营养性变形虫对环磷酸腺苷（cAMP）的趋化反应非常微弱，而聚集的变形虫对其反应异常强烈。有人认为，这种新因子可能用于寻找食物，而负责聚集的趋化物质cAMP是该物种的聚集素。重要的是，变形虫对这两种趋化剂的反应具有不同的阶段特异性。
