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脊髓灰质炎病毒核糖核酸的分子量

Molecular weight of poliovirus ribonucleic acid.

作者信息

Granboulan N, Girard M

出版信息

J Virol. 1969 Oct;4(4):475-9. doi: 10.1128/JVI.4.4.475-479.1969.

Abstract

Purified poliovirus single- and double-stranded ribonucleic acids (RNA) were examined by electron microscopy. The length of both molecules was found to be 2.37 mum. The uncorrected sedimentation coefficient for single-stranded RNA is 33S, as compared to 27S for the RNA of tobacco mosaic virus. It is calculated from these results that the molecular weight of the sodium form of poliovirus is 2.6 x 10(6) daltons.

摘要

通过电子显微镜检查了纯化的脊髓灰质炎病毒单链和双链核糖核酸(RNA)。发现这两种分子的长度均为2.37μm。单链RNA未经校正的沉降系数为33S,而烟草花叶病毒RNA的沉降系数为27S。根据这些结果计算得出,脊髓灰质炎病毒钠型的分子量为2.6×10⁶道尔顿。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4927/375896/8246b53b1a51/jvirol00310-0160-a.jpg

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