合成双链RNA（聚腺苷酸和聚尿苷酸以及聚肌苷酸和聚胞苷酸）对单纯疱疹病毒的抑制作用。
Inhibition of herpes simplex virus by synthetic double-stranded RNA (polyriboadenylic and polyribouridylic acids and polyriboinosinic and polyribocytidylic acids).
作者信息
Hamilton L D, Babcock V I, Southam C M
出版信息
Proc Natl Acad Sci U S A. 1969 Nov;64(3):878-83. doi: 10.1073/pnas.64.3.878.
Abstract
Two-stranded polyriboadenylic and polyribouridylic acids and polyriboinosinic and polyribocytidylic acids protect against herpes simplex virus-induced cytopathogenicity in HEp 2 cultures, systemic herpes simplex virus infection in mice, and herpes simplex virus-induced keratoconjunctivitis in rabbits.
摘要
双链聚核糖腺苷酸和聚核糖尿苷酸以及聚核糖肌苷酸和聚核糖胞苷酸可预防单纯疱疹病毒在HEp 2培养物中引起的细胞致病性、在小鼠中引起的全身性单纯疱疹病毒感染以及在兔中引起的单纯疱疹病毒性角膜结膜炎。
相似文献
1
Inhibition of herpes simplex virus by synthetic double-stranded RNA (polyriboadenylic and polyribouridylic acids and polyriboinosinic and polyribocytidylic acids).合成双链RNA（聚腺苷酸和聚尿苷酸以及聚肌苷酸和聚胞苷酸）对单纯疱疹病毒的抑制作用。
Proc Natl Acad Sci U S A. 1969 Nov;64(3):878-83. doi: 10.1073/pnas.64.3.878.
2
3
Herpetic keratoconjunctivitis: therapy with synthetic double-stranded RNA.疱疹性角膜结膜炎：用合成双链核糖核酸进行治疗
Science. 1968 Nov 15;162(3855):811-3. doi: 10.1126/science.162.3855.811.
4
Protection against herpes virus and encephalomyocarditis virus encephalitis with a double-stranded RNA inducer of interferon.使用干扰素的双链RNA诱导剂预防疱疹病毒和脑心肌炎病毒脑炎
Proc Soc Exp Biol Med. 1970 Feb;133(2):684-7. doi: 10.3181/00379727-133-34544.
5
Nucleic acids. 3. Antiviral activity of nucleotides and dinucleoside phosphates containing ara-cytidine.核酸。3. 含阿糖胞苷的核苷酸和二核苷磷酸的抗病毒活性。
J Med Chem. 1967 Sep;10(5):777-82. doi: 10.1021/jm00317a005.
6
Hyperpotentiation by synthetic double-stranded RNA of antibody responses to influenza virus vaccine in adjuvant 65.佐剂65中合成双链RNA对流感病毒疫苗抗体反应的超增强作用。
Proc Soc Exp Biol Med. 1969 Jul;131(3):809-17. doi: 10.3181/00379727-131-33983.
7
Foot-and-mouth disease virus inhibition induced in mice by synthetic double-stranded RNA (polyriboinosinic and polyribocytidylic acids).合成双链RNA（聚肌苷酸和聚胞苷酸）在小鼠中诱导产生的口蹄疫病毒抑制作用。
Proc Natl Acad Sci U S A. 1969 Sep;64(1):81-6. doi: 10.1073/pnas.64.1.81.
8
Inhibition of Shope fibroma virus replication by polyriboinosinic acid: polyribocytidylic acid.聚肌苷酸：聚胞苷酸对肖普纤维瘤病毒复制的抑制作用
Proc Soc Exp Biol Med. 1970 Jul;134(3):752-5. doi: 10.3181/00379727-134-34876.
9
Inhibition of growth of Euglena and Astasia by primycin and prevention of the effect by polynucleotides.竹桃霉素对眼虫和阿斯塔虫生长的抑制作用以及多核苷酸对该作用的预防作用。
Arch Biochem Biophys. 1965 Sep;111(3):635-45. doi: 10.1016/0003-9861(65)90245-6.
10
Influence of synthetic double-stranded ribonucleic acid, poly I:C, on Friend leukemia in mice.合成双链核糖核酸聚肌胞苷酸（poly I:C）对小鼠Friend白血病的影响。
Proc Soc Exp Biol Med. 1969 Nov;132(2):602-7. doi: 10.3181/00379727-132-34269.
引用本文的文献
1
Role of adrenal cortical function in toxicity of polyriboinosinic-polyribocytidylic acid and its component homopolymers.肾上腺皮质功能在聚肌苷酸-聚胞苷酸及其组分同聚物毒性中的作用。
Proc Natl Acad Sci U S A. 1970 Sep;67(1):180-4. doi: 10.1073/pnas.67.1.180.
2
Influence of interferon on the replication of oncogenic herpesviruses in tissue cultures and in nonhuman primates.干扰素对致癌性疱疹病毒在组织培养物及非人类灵长类动物中复制的影响。
Med Microbiol Immunol. 1974;160(4):285-94. doi: 10.1007/BF02121444.
3
4
Antiviral activity and side effects of polyriboinosinic-cytidylic acid complexes as affected by molecular size.多聚肌苷酸-胞苷酸复合物的抗病毒活性及副作用受分子大小的影响
Proc Natl Acad Sci U S A. 1972 Apr;69(4):842-6. doi: 10.1073/pnas.69.4.842.
5
Herpesvirus hominis infection in newborn mice: treatment with interferon inducer polyinosinic-polycytidylic acid.新生小鼠人疱疹病毒感染：用干扰素诱导剂聚肌苷酸-聚胞苷酸进行治疗。
Antimicrob Agents Chemother. 1975 Jun;7(6):793-800. doi: 10.1128/AAC.7.6.793.
6
Inhibition of herpes simplex virus strains isolated from herpetic keratitis by polyinosinic acid-polycytidylic acid.聚肌苷酸-聚胞苷酸对从疱疹性角膜炎分离出的单纯疱疹病毒株的抑制作用。
Antimicrob Agents Chemother. 1977 May;11(5):797-802. doi: 10.1128/AAC.11.5.797.
7
Antiviral effect of pyran against systemic infection of mice with herpes simplex virus type 2.吡喃对小鼠2型单纯疱疹病毒全身感染的抗病毒作用。
Antimicrob Agents Chemother. 1976 Jul;10(1):28-33. doi: 10.1128/AAC.10.1.28.
本文引用的文献
1
IDU therapy of herpes simplex.单纯疱疹的注射吸毒疗法。 （不过从医学常理看，这个表述不太符合常见医学内容，可能原文有误，正常应该是关于单纯疱疹的某种规范治疗方法表述，比如“Intermittent dosing therapy of herpes simplex”之类，单纯“IDU therapy”这样表述容易误解，这里是按照字面翻译）
Arch Ophthalmol. 1962 May;67:583-91. doi: 10.1001/archopht.1962.00960020583012.
2
DECREASED PATHOGENICITY FOR RABBIT SKIN OF IDU-RESISTANT VACCINIA VIRUS.耐异烟肼痘苗病毒对兔皮肤致病性降低
Virology. 1965 May;26:154-5. doi: 10.1016/0042-6822(65)90039-5.
3
Culture characteristics of four permanent lines of human cancer cells.四种人类癌细胞永久系的培养特性
Cancer Res. 1955 Oct;15(9):598-602.
4
DNA: models and reality.DNA：模型与现实
Nature. 1968 May 18;218(5142):633-7. doi: 10.1038/218633a0.
5
Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes.干扰素与宿主抗性的诱导剂。II. 多链合成多核苷酸复合物。
Proc Natl Acad Sci U S A. 1967 Sep;58(3):1004-10. doi: 10.1073/pnas.58.3.1004.
6
Inducers of interferon and host resistance. I. Double-stranded RNA from extracts of Penicillium funiculosum.干扰素与宿主抗性的诱导剂。I. 来自绳状青霉提取物的双链RNA。
Proc Natl Acad Sci U S A. 1967 Aug;58(2):782-9. doi: 10.1073/pnas.58.2.782.
7
Foot-and-mouth disease virus inhibition induced in mice by synthetic double-stranded RNA (polyriboinosinic and polyribocytidylic acids).合成双链RNA（聚肌苷酸和聚胞苷酸）在小鼠中诱导产生的口蹄疫病毒抑制作用。
Proc Natl Acad Sci U S A. 1969 Sep;64(1):81-6. doi: 10.1073/pnas.64.1.81.
8
Herpetic keratoconjunctivitis: therapy with synthetic double-stranded RNA.疱疹性角膜结膜炎：用合成双链核糖核酸进行治疗
Science. 1968 Nov 15;162(3855):811-3. doi: 10.1126/science.162.3855.811.
9
Inducers of interferon and host resistance. 3. Double-stranded RNA from reovirus type 3 virions (reo 3-RNA).干扰素与宿主抵抗力的诱导剂。3. 来自呼肠孤病毒3型病毒粒子的双链RNA（呼肠孤病毒3型RNA）
Proc Natl Acad Sci U S A. 1967 Oct;58(4):1719-22. doi: 10.1073/pnas.58.4.1719.
10
Inducers of interferon and host resistance, IV. Double-stranded replicative form RNA (MS2-Ff-RNA) from E. coli infected with MS2 coliphage.干扰素与宿主抗性的诱导剂，IV. 感染MS2噬菌体的大肠杆菌的双链复制型RNA（MS2-Ff-RNA）
Proc Natl Acad Sci U S A. 1967 Nov;58(5):2102-8. doi: 10.1073/pnas.58.5.2102.
Zotero 插件