Duesberg P H, Vogt P K
Proc Natl Acad Sci U S A. 1969 Nov;64(3):939-46. doi: 10.1073/pnas.64.3.939.
Preinfection of chick embryo fibroblasts with an avian tumor virus does not eliminate the requirement of early DNA synthesis for other avian tumor viruses superinfecting the same cells several days after the primary inoculum. The function served by the early DNA in avian tumor virus infection either fails to persist into late infection or is genetically specific for each viral type.
用禽肿瘤病毒对鸡胚成纤维细胞进行感染前处理,并不能消除早期DNA合成对于在初次接种几天后再次感染同一细胞的其他禽肿瘤病毒的必要性。禽肿瘤病毒感染中早期DNA所发挥的功能,要么无法持续到感染后期,要么对每种病毒类型具有遗传特异性。