Verdugo P, Hinds T R, Vincenzi F F
Pediatr Res. 1979 Feb;13(2):131-5. doi: 10.1203/00006450-197902000-00009.
The effect of 7 cystic fibrosis sera and 4 normal sera was investigated in 37 cultures of ciliated epithelium of the rabbit trachea. Serum was introduced in the Rose culture chambers in a concentration of 10% by volume. The frequency of ciliary beat was monitored by laser light-scattering spectroscopy. The results show that the response of cilia to sera can be well characterized by laser light scattering. Our preliminary evidence suggests that an early increase in the frequency of ciliary beat, followed by rapid arrest of ciliary activity, is a sensitive and characteristic response produced by cystic fibrosis serum, and not by normal serum.
在37个兔气管纤毛上皮培养物中研究了7份囊性纤维化血清和4份正常血清的作用。血清以体积浓度10%引入罗斯培养室。通过激光散射光谱法监测纤毛摆动频率。结果表明，纤毛对血清的反应可以通过激光散射很好地表征。我们的初步证据表明，纤毛摆动频率早期增加，随后纤毛活动迅速停止，是囊性纤维化血清而非正常血清产生的一种敏感且具有特征性的反应。
